CAS 136705-64-1: (-)-DUPHOS

Description: (-)-DUPHOS, with the CAS number 136705-64-1, is a chiral phosphine ligand commonly used in asymmetric catalysis. It is characterized by its ability to form stable complexes with transition metals, enhancing the selectivity and efficiency of various chemical reactions, particularly in the synthesis of enantiomerically pure compounds. The structure of (-)-DUPHOS features a phosphine core with two bulky substituents, which contributes to its steric and electronic properties, making it effective in catalyzing reactions such as hydrogenation and cross-coupling. Its chirality is crucial for inducing asymmetry in reactions, allowing for the preferential formation of one enantiomer over another. Additionally, (-)-DUPHOS is known for its compatibility with a range of metal catalysts, including palladium and rhodium, and is widely utilized in both academic and industrial settings for the development of pharmaceuticals and fine chemicals. Safety data indicates that, like many phosphine compounds, it should be handled with care due to potential toxicity and reactivity.

Formula: C₂₂H₃₆P₂

InChI: InChI=1S/C22H36P2/c1-5-17-13-14-18(6-2)23(17)21-11-9-10-12-22(21)24-19(7-3)15-16-20(24)8-4/h9-12,17-20H,5-8,13-16H2,1-4H3/t17-,18-,19-,20-/m1/s1

InChI key: InChIKey=GVVCHDNSTMEUCS-UAFMIMERSA-N

SMILES: C=1C=CC(=C(C1)P2C(CC)CCC2CC)P3C(CC)CCC3CC

Synonyms:

• (-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene(r,r)-et-duphos
• (-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene,98+%(R,R)-Et-DUPHOS
• (-)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene, Kanata purity
• (-)-Duphos
• (2R,2'R,5R,5'R)-2,2'-5,5'-Tetraethyl-1,1'-(1,2-Phenylene)Diphospholane
• (2R,2'R,5R,5'R)-2,2'-5,5'-Tetraethyl-1,1'-(O-Phenylene)Diphospholane
• (2R,2′R,5R,5′R)-1,1′-(1,2-Phenylene)bis[2,5-diethylphospholane]
• (2R,5R,2'R,5'R)-1,1'-benzene-1,2-diylbis(2,5-diethylphospholane)
• (R,R)-Et-Duphos
• (R,R)-EtDuPHOS
• (R,R)-Ethyl-Duphos
• Phospholane, 1,1′-(1,2-phenylene)bis[2,5-diethyl-, (2R,2′R,5R,5′R)-
• (-)-1,2-Bis(2R,5R-2,5-diethylphospholano)benzene

(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene, 98+% (R,R)-Et-DUPHOS

CAS: 136705-64-1

• Formula: C₂₂H₃₆P₂
• Purity: 98+%
• Color and Shape: colorless oil
• Molecular weight: 362.48

Phospholane, 1,1'-(1,2-phenylene)bis[2,5-diethyl-, (2R,2'R,5R,5'R)-

CAS: 136705-64-1

• Formula: C₂₂H₃₆P₂
• Purity: 97%
• Color and Shape: Liquid
• Molecular weight: 362.4687619999998

1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLAN-1-YL)BENZENE

CAS: 136705-64-1

• Purity: 98%
• Color and Shape: Liquid, Viscous
• Molecular weight: 362.4779968261719

(-)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene

CAS: 136705-64-1

(-)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene (DIPE) is a chiral ligand that binds to metal ions in a trans configuration. …

• Formula: C₂₂H₃₆P₂
• Purity: Min. 95%
• Molecular weight: 362.47 g/mol