Description:Fmoc-D-Ile-OH, or 9-fluorenylmethoxycarbonyl-D-isoleucine, is a protected amino acid commonly used in peptide synthesis. The Fmoc group serves as a protective moiety for the amino group, allowing for selective reactions during the synthesis process. This compound features a D-isoleucine residue, which is one of the two enantiomers of isoleucine, an essential amino acid. The presence of the Fmoc group enhances the solubility of the compound in organic solvents, facilitating its use in various chemical reactions. Fmoc-D-Ile-OH is typically utilized in solid-phase peptide synthesis, where it can be sequentially added to growing peptide chains. Its stability under basic conditions and compatibility with various coupling reagents make it a valuable building block in the synthesis of peptides and proteins. Additionally, the compound is characterized by its relatively low toxicity and is generally handled with standard laboratory safety precautions. Overall, Fmoc-D-Ile-OH is an important tool in the field of peptide chemistry and biochemistry.
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