CAS 143824-77-5: Fmoc-Arg(Boc)2-OH
Description:Fmoc-Arg(Boc)2-OH, with the CAS number 143824-77-5, is a protected amino acid derivative commonly used in peptide synthesis. It features a phenylmethoxycarbonyl (Fmoc) protecting group on the amino group of arginine, along with two tert-butyloxycarbonyl (Boc) groups protecting the guanidino group. This compound is characterized by its stability under basic conditions, making it suitable for solid-phase peptide synthesis. The Fmoc group allows for easy removal under mild basic conditions, facilitating the sequential addition of amino acids in peptide chains. The presence of the Boc groups provides additional protection, ensuring that the guanidino functionality remains intact during the synthesis process. Fmoc-Arg(Boc)2-OH is typically utilized in the preparation of peptides that require specific modifications or functionalities, particularly in the fields of biochemistry and medicinal chemistry. Its solubility in organic solvents and stability under various reaction conditions make it a valuable intermediate in the synthesis of complex peptides and proteins.
Formula:C31H40N4O8
InChI:InChI=1/C31H40N4O8/c1-30(2,3)42-28(39)34-26(35-29(40)43-31(4,5)6)32-17-11-16-24(25(36)37)33-27(38)41-18-23-21-14-9-7-12-19(21)20-13-8-10-15-22(20)23/h7-10,12-15,23-24H,11,16-18H2,1-6H3,(H,33,38)(H,36,37)(H2,32,34,35,39,40)/t24-/m0/s1
- Synonyms:
- N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N~5~-(2,2,10,10-tetramethyl-4,8-dioxo-3,9-dioxa-5,7-diazaundecan-6-ylidene)-L-ornithine