CAS 144742-33-6: 5'-O-ACETYL-3'-AZIDO-N2-PALMITOYL-2',3'-DIDEOXYGUANOSINE

Description: 5'-O-Acetyl-3'-azido-N2-palmitoyl-2',3'-dideoxyguanosine, with the CAS number 144742-33-6, is a synthetic nucleoside analog characterized by its structural modifications that enhance its pharmacological properties. This compound features an azido group at the 3' position, which is significant for its potential use in antiviral therapies, particularly against HIV. The presence of the palmitoyl group at the N2 position increases its lipophilicity, facilitating cellular uptake and enhancing its bioavailability. The acetyl group at the 5' position serves to protect the hydroxyl group, influencing the compound's stability and reactivity. As a dideoxy nucleoside, it lacks the 2' and 3' hydroxyl groups, which is crucial for its mechanism of action as a chain terminator during DNA synthesis. Overall, this compound's unique structural features contribute to its potential as a therapeutic agent in the treatment of viral infections, particularly in the context of nucleoside reverse transcriptase inhibitors.

Formula: C₂₈H₄₄N₈O₅

Synonyms:

• 5'-O-Acetyl-3'-Azido-N2-Palmitoyl-2',3'-Dideoxy-D-Guanosine
• 5'-O-Acetyl-3'-azido-2',3'-dideoxy-N2-palmitoyl-D-guanosine

5''-O-Acetyl-3''-azido-2'',3''-dideoxy-N2-palmitoylguanosine

CAS: 144742-33-6

5'-O-Acetyl-3'-azido-2',3'-dideoxy-N2-palmitoylguanosine

CAS: 144742-33-6

5'-O-Acetyl-3'-azido-2',3'-dideoxy-N2-palmitoylguanosine is a novel antiviral and anticancer agent. It is an analogue of the natural …

• Formula: C₂₈H₄₄N₈O₅
• Purity: Min. 95%
• Molecular weight: 572.7 g/mol