CAS 144822-48-0: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

Description: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione, with CAS number 144822-48-0, is a synthetic compound that belongs to the class of nucleoside analogs. This substance features a pyrimidinedione core, which is modified with a 2-deoxy-2-fluoro-beta-D-arabinofuranosyl moiety, enhancing its potential for biological activity. The presence of the bis(4-methoxyphenyl)phenylmethyl group contributes to its lipophilicity, potentially influencing its pharmacokinetic properties. The compound is of interest in medicinal chemistry, particularly for its potential antiviral or anticancer activities, as nucleoside analogs often interfere with nucleic acid synthesis. Its structural complexity suggests that it may exhibit unique interactions with biological targets, making it a candidate for further research in drug development. However, detailed studies on its efficacy, safety, and mechanism of action are essential for understanding its potential therapeutic applications.

Formula: C₃₁H₃₁FN₂O₇

InChI: InChI=1/C31H31FN2O7/c1-19-17-34(30(37)33-28(19)36)29-26(32)27(35)25(41-29)18-40-31(20-7-5-4-6-8-20,21-9-13-23(38-2)14-10-21)22-11-15-24(39-3)16-12-22/h4-17,25-27,29,35H,18H2,1-3H3,(H,33,36,37)/t25-,26+,27-,29?/m1/s1

Synonyms:

• 1-{5-O-[Bis-(4-methoxyphenyl)-phenylmethyl]-2-deoxy-2-fluoro--D-arabinofuranosyl}-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-[(3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-fluoro-4-hydroxy-tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-b-D-arabinouridine

CAS: 144822-48-0

Nucleoside Derivatives - Protected nucleosides w/NH2/OH open; Fluoro-modified nucleosides

• Formula: C₃₁H₃₁FN₂O₇
• Color and Shape: Liquid
• Molecular weight: 562.59

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine

CAS: 144822-48-0

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine is a synthetic nucleoside that is used to synthesize DNA and RNA. It is …

• Formula: C₃₁H₃₁FN₂O₇
• Purity: Min. 95%
• Molecular weight: 562.6 g/mol