CAS 144875-48-9: Resiquimod

Description: Resiquimod is a synthetic imidazoquinoline compound that acts as an immune response modifier, primarily functioning as a toll-like receptor (TLR) 7 and TLR8 agonist. It is characterized by its ability to stimulate the innate immune system, leading to the activation of various immune cells, including dendritic cells and macrophages. This activation results in the production of pro-inflammatory cytokines and enhances both the humoral and cellular immune responses. Resiquimod is often explored for its potential therapeutic applications in treating viral infections, certain cancers, and skin conditions, such as actinic keratosis and superficial basal cell carcinoma. The compound is typically administered topically, and its formulation may include various excipients to enhance skin penetration and bioavailability. Due to its immunomodulatory effects, Resiquimod has been the subject of numerous clinical studies, highlighting its role in enhancing vaccine efficacy and its potential as an adjuvant in immunotherapy. Safety profiles indicate that it may cause local skin reactions, which are generally mild and transient.

Formula: C₁₇H₂₂N₄O₂

InChI: InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19)

InChI key: InChIKey=BXNMTOQRYBFHNZ-UHFFFAOYSA-N

SMILES: OC(C)(C)CN1C(=NC=2C(=NC=3C=CC=CC3C21)N)COCC

Synonyms:

• 1-[4-Amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
• 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-α,α-dimethyl-
• 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline
• 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
• 4-Amino-2-(ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
• R-848
• Resimiquimod
• Resiquimod
• S-28463
• Vml-600

Resiquimod

CAS: 144875-48-9

• Formula: C₁₇H₂₂N₄O₂
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 314.39

1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-α,α-dimethyl-

CAS: 144875-48-9

• Formula: C₁₇H₂₂N₄O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 314.3822

Resiquimod

CAS: 144875-48-9

• Formula: C₁₇H₂₂N₄O₂
• Color and Shape: Off-White Solid
• Molecular weight: 314.39

Resiquimod-d5

CAS: 144875-48-9

• Formula: C₁₇H₁₇D₅N₄O₂
• Color and Shape: Off-White Solid
• Molecular weight: 319.42

Resiquimod

CAS: 144875-48-9

Resiquimod (R848) is a TLR7/TLR8 agonist. Resiquimod is an immunomodulator with antitumor and antiviral activity. …

• Formula: C₁₇H₂₂N₄O₂
• Purity: 99.62% - 99.95%
• Color and Shape: Solid
• Molecular weight: 314.38

1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol

CAS: 144875-48-9

• Formula: C₁₇H₂₂N₄O₂
• Purity: 98%
• Color and Shape: off-white solid
• Molecular weight: 314.38g/mol

Resiquimod

CAS: 144875-48-9

• Formula: C₁₇H₂₂N₄O₂
• Purity: ≥ 98.0%
• Color and Shape: Off-white solid
• Molecular weight: 314.38

1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol

CAS: 144875-48-9

• Purity: 95.0%
• Color and Shape: Solid, Powder
• Molecular weight: 314.3890075683594

Resiquimod

CAS: 144875-48-9

Resiquimod is a synthetic imidazoquinoline that has potent immunological activities, including induction of cytokines and …

• Formula: C₁₇H₂₂N₄O₂
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 314.38 g/mol

Resiquimod

CAS: 144875-48-9

Applications Resiquimod is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows …

• Formula: C₁₇H₂₂N₄O₂
• Color and Shape: White Solid
• Molecular weight: 314.38