CAS 145375-43-5: Mitiglinide

Description: Mitiglinide is an oral hypoglycemic agent primarily used in the management of type 2 diabetes mellitus. It belongs to the class of medications known as meglitinides, which function by stimulating insulin secretion from the pancreatic beta cells in response to meals, thereby helping to control postprandial blood glucose levels. Mitiglinide has a rapid onset of action, making it effective for controlling blood sugar spikes after eating. The substance is characterized by its relatively short half-life, necessitating multiple daily doses to maintain glycemic control. It is typically administered shortly before meals and is often used in conjunction with other antidiabetic medications. Mitiglinide's chemical structure includes a unique combination of functional groups that contribute to its pharmacological activity. As with any medication, potential side effects may include hypoglycemia, gastrointestinal disturbances, and weight gain, highlighting the importance of monitoring and individualized treatment plans for patients. Overall, mitiglinide represents a valuable option in the therapeutic arsenal for managing type 2 diabetes.

Formula: C₁₉H₂₅NO₃

InChI: InChI=1S/C19H25NO3/c21-18(20-12-15-8-4-5-9-16(15)13-20)11-17(19(22)23)10-14-6-2-1-3-7-14/h1-3,6-7,15-17H,4-5,8-13H2,(H,22,23)/t15-,16+,17-/m0/s1

InChI key: InChIKey=WPGGHFDDFPHPOB-BBWFWOEESA-N

SMILES: O=C(O)C(CC=1C=CC=CC1)CC(=O)N2CC3CCCCC3C2

Synonyms:

• 2H-Isoindole-2-butanoic acid, octahydro-γ-oxo-α-(phenylmethyl)-, [2(S)-cis]-
• Mitiglinide
• (αS,3aR,7aS)-Octahydro-γ-oxo-α-(phenylmethyl)-2H-isoindole-2-butanoic acid
• 2H-Isoindole-2-butanoic acid, octahydro-γ-oxo-α-(phenylmethyl)-, (αS,3aR,7aS)-
• [2(S)-cis]-Octahydro-gamma-oxo-alpha-(phenylmethyl)-2H-isoindole-2-butanoic acid
• (2S)-2-benzyl-4-[(3aR,7aS)-octahydro-2H-isoindol-2-yl]-4-oxobutanoic acid
• 2-benzyl-4-(octahydro-2H-isoindol-2-yl)-4-oxobutanoic acid

Mitiglinide

CAS: 145375-43-5

• Formula: C₁₉H₂₅NO₃
• Molecular weight: 315.42

Mitiglinide

CAS: 145375-43-5

Mitiglinide (KAD-1229), an insulinotropic ATP-sensitive K+ channel antagonist, targets Kir6.2/SUR1; used in type 2 diabetes …

• Formula: C₁₉H₂₅NO₃
• Color and Shape: Solid
• Molecular weight: 315.41

Mitiglinide

CAS: 145375-43-5

Voltage-dependent K+ channel opener; insulinotropic sulfonylurea receptor ligand

• Purity: Min. 95%