CAS 14663-23-1: Dantrolene sodium

Description: Dantrolene sodium is a muscle relaxant primarily used in the treatment of conditions such as malignant hyperthermia and spasticity associated with neurological disorders. It functions by inhibiting calcium release from the sarcoplasmic reticulum of skeletal muscle, thereby reducing muscle contraction. This compound is a white to off-white crystalline powder that is soluble in water and has a pH range that is typically neutral to slightly alkaline. Dantrolene sodium is administered intravenously or orally, depending on the clinical scenario. Its chemical structure includes a dantrolene moiety, which is a derivative of hydantoin, and it is often formulated as the sodium salt to enhance solubility. The pharmacokinetics of dantrolene involve hepatic metabolism, and it is important to monitor liver function during prolonged therapy due to potential hepatotoxicity. Overall, dantrolene sodium is a critical medication in emergency and chronic care settings, requiring careful dosing and monitoring to ensure patient safety and efficacy.

Formula: C₁₄H₁₀N₄O₅·Na

InChI: InChI=1S/C14H10N4O5.Na/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22;/h1-7H,8H2,(H,16,19,20);

InChI key: InChIKey=BDZCLIOURDFSFQ-UHFFFAOYSA-N

SMILES: [Na].O=C1NC(=O)CN1N=CC=2OC(=CC2)C=3C=CC(=CC3)N(=O)=O

Synonyms:

• 1-[5-(-4-Nitrophenyl)furfurylideneamino]imidazolidine-2,4-dione sodium
• 1-[[5-(p-Nitrophenyl)furfurylidene]amino]-hydantoin sodium salt
• 2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt
• 2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt (1:1)
• 2,4-imidazolidinedione, 1-[[(1E)-[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt
• Dantrium
• Dantrolene Na
• Dantrolene, Sodium Salt
• F 440
• Hydantoin, 1-[[5-(p-nitrophenyl)furfurylidene]amino]-, sodium salt
• Ryanodex
• Sodium 3-({[5-(4-Nitrophenyl)Furan-2-Yl]Methylidene}Amino)-2,5-Dioxoimidazolidin-1-Ide
• Sodium dantrolene
• sodium 1-({(1E)-[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)-4-oxo-4,5-dihydro-1H-imidazol-2-olate
• Dantrolene sodium

Dantrolene Sodium Salt Hydrate

CAS: 14663-23-17261-97-4

• Formula: C₁₄H₉N₄NaO₅·xH₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: Orange to Brown powder to crystal
• Molecular weight: 336.24 (as Anhydrous)

Dantrolene sodium salt

CAS: 14663-23-1

Inhibits intracellular calcium release from the sarcoplasmic reticulum This Thermo Scientific Chemicals brand product was …

• Formula: C₁₄H₉N₄NaO₅
• Molecular weight: 336.23

Dantrolene sodium salt

CAS: 14663-23-1

• Formula: C₁₄H₁₀N₄NaO₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 337.24277

Dantrolene sodium

CAS: 14663-23-1

Dantrolene sodium treats spasticity by disrupting muscle contraction; not central in action, grouped with central …

• Formula: C₁₄H₉N₄NaO₅
• Purity: 100% - 99.11%
• Color and Shape: Coa
• Molecular weight: 336.23

Dantrolene sodium salt

CAS: 14663-23-1

• Formula: C₁₄H₉N₄NaO₅·xH₂O
• Purity: ≥ 98.0% (anhydrous basis)
• Color and Shape: Orange to dark orange crystalline powder
• Molecular weight: 336.23 (anhydrous)

Dantrolene sodium salt, USP grade

CAS: 14663-23-1

• Formula: C₁₄H₉N₄NaO₅·xH₂O
• Purity: 98.0 - 102.0 % (anhydrous basis)
• Color and Shape: Orange to dark orange crystalline powder
• Molecular weight: 336.23 (anhydrous)

Sodium 3-(((5-(4-Nitrophenyl)Furan-2-Yl)Methylene)Amino)-2,5-Dioxoimidazolidin-1-Ide

CAS: 14663-23-1

• Purity: 98%
• Molecular weight: 336.23g/mol

Dantrolene Sodium Salt

CAS: 14663-23-1

• Formula: C₁₄H₉N₄O₅·Na
• Molecular weight: 313.25 22.99

1-[[5-(p-Nitrophenyl)furfurylidene]amino]-hydantoin sodium

CAS: 14663-23-1

Please enquire for more information about 1-[[5-(p-Nitrophenyl)furfurylidene]amino]-hydantoin sodium including the price, delivery time and more …

• Formula: C₁₄H₁₀N₄O₅•Na
• Purity: Min. 95%
• Color and Shape: Yellow Powder
• Molecular weight: 337.24 g/mol