CAS 147197-81-7: 7-fluoro-2-phenyl-4-quinolone

Description: 7-Fluoro-2-phenyl-4-quinolone is a synthetic compound belonging to the quinolone class of antibiotics, characterized by its bicyclic structure that includes a fused benzene and pyridine ring. This compound features a fluorine atom at the 7-position and a phenyl group at the 2-position, which contribute to its pharmacological properties. It exhibits antibacterial activity, primarily against Gram-negative bacteria, by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. The presence of the fluorine atom enhances its lipophilicity, potentially improving its bioavailability and efficacy. Additionally, 7-fluoro-2-phenyl-4-quinolone may possess anti-inflammatory and analgesic properties, making it a subject of interest in medicinal chemistry. Its solubility and stability in various solvents can vary, influencing its formulation and application in therapeutic contexts. As with many quinolones, attention must be given to potential side effects and resistance mechanisms that may arise with its use. Overall, this compound represents a significant area of research in developing effective antimicrobial agents.

Formula: C₁₅H₁₀FNO

InChI: InChI=1/C15H10FNO/c16-11-6-7-12-14(8-11)17-13(9-15(12)18)10-4-2-1-3-5-10/h1-9H,(H,17,18)

Synonyms:

• 4(1H)-Quinolinone, 7-fluoro-2-phenyl-
• 7-fluoro-2-phenylquinolin-4(1H)-one
• 7-Fluoro-2-phenyl-4-quinolone

4(1H)-Quinolinone, 7-fluoro-2-phenyl-

CAS: 147197-81-7

• Formula: C₁₅H₁₀FNO
• Molecular weight: 239.2444

7-Fluoro-2-phenyl-1,4-dihydroquinolin-4-one

CAS: 147197-81-7

• Purity: 98%
• Molecular weight: 239.24899291992188

7-Fluoro-2-Phenyl-1H-Quinolin-4-One

CAS: 147197-81-7

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• Formula: C₁₅H₁₀FNO
• Purity: Min. 95%
• Molecular weight: 239.24 g/mol