CAS: 147318-81-8 - Kynostatin 272

Formula: C₃₃H₄₁N₅O₆S₂

InChI: InChI=1S/C33H41N5O6S2/c1-33(2,3)37-31(42)26-19-46-20-38(26)32(43)29(40)24(15-21-9-6-5-7-10-21)36-30(41)25(18-45-4)35-28(39)17-44-27-12-8-11-22-16-34-14-13-23(22)27/h5-14,16,24-26,29,40H,15,17-20H2,1-4H3,(H,35,39)(H,36,41)(H,37,42)/t24-,25-,26-,29-/m0/s1

InChI key: InChIKey=NJBBLOIWMSYVCQ-VZTVMPNDSA-N

SMILES: O=C(NC(C(=O)NC(CC=1C=CC=CC1)C(O)C(=O)N2CSCC2C(=O)NC(C)(C)C)CSC)COC3=CC=CC=4C=NC=CC34

Synonyms:

• (4R)-N-(1,1-Dimethylethyl)-3-[(2S,3S)-2-hydroxy-3-[[(2R)-2-[[(5-isoquinolinyloxy)acetyl]amino]-3-(methylthio)-1-oxopropyl]amino]-1-oxo-4-phenylbutyl]-4-thiazolidinecarboxamide
• 4-Thiazolidinecarboxamide, N-(1,1-dimethylethyl)-3-[(2S,3S)-2-hydroxy-3-[[(2R)-2-[[(5-isoquinolinyloxy)acetyl]amino]-3-(methylthio)-1-oxopropyl]amino]-1-oxo-4-phenylbutyl]-, (4R)-
• 4-Thiazolidinecarboxamide, N-(1,1-dimethylethyl)-3-[2-hydroxy-3-[[2-[[(5-isoquinolinyloxy)acetyl]amino]-3-(methylthio)-1-oxopropyl]amino]-1-oxo-4-phenylbutyl]-, [4R-[3[2S*,3S*(R*)],4R*]]-
• Kynostatin
• KNI 272

KNI-272

CAS: 147318-81-8

Kynostatin-272 is a HIV protease inhibitor. KNI-272 blocked the maturation of viral particles.

• Formula: C₃₃H₄₁N₅O₆S₂
• Color and Shape: Solid
• Molecular weight: 667.84