CAS 149289-30-5: N-Desmethylvenlafaxine

Description: N-Desmethylvenlafaxine, with the CAS number 149289-30-5, is a chemical compound that serves as a metabolite of the antidepressant venlafaxine. It is classified as a phenethylamine and is known for its role in the treatment of major depressive disorder and anxiety disorders. The compound exhibits a dual mechanism of action, primarily functioning as a serotonin-norepinephrine reuptake inhibitor (SNRI), which enhances the levels of serotonin and norepinephrine in the synaptic cleft, thereby improving mood and alleviating anxiety. N-Desmethylvenlafaxine is characterized by its moderate lipophilicity, which influences its pharmacokinetic properties, including absorption and distribution in the body. The substance is typically administered in oral form and is subject to metabolic processes in the liver, where it is further converted into other metabolites. Its safety profile and efficacy are well-documented, making it a significant focus in pharmacological research related to mental health treatments. As with any medication, potential side effects and interactions with other drugs should be considered.

Formula: C₁₆H₂₅NO₂

InChI: InChI=1S/C16H25NO2/c1-17-12-15(16(18)10-4-3-5-11-16)13-6-8-14(19-2)9-7-13/h6-9,15,17-18H,3-5,10-12H2,1-2H3

InChI key: InChIKey=MKAFOJAJJMUXLW-UHFFFAOYSA-N

SMILES: OC1(CCCCC1)C(C2=CC=C(OC)C=C2)CNC

Synonyms:

• 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexan-1-ol
• 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol
• Cyclohexanol, 1-[1-(4-methoxyphenyl)-2-(methylamino)ethyl]-
• N-Desmethylvenlafaxine
• Norvenlafaxine

Cyclohexanol, 1-[1-(4-methoxyphenyl)-2-(methylamino)ethyl]-

CAS: 149289-30-5

• Formula: C₁₆H₂₅NO₂
• Color and Shape: Solid
• Molecular weight: 263.3752

Venlafaxine-N-desmethyl

CAS: 149289-30-5

• Formula: C₁₆H₂₅NO₂
• Color and Shape: Neat
• Molecular weight: 263.38

rac N-Desmethyl Venlafaxine

CAS: 149289-30-5

Applications A metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant. …

• Formula: C₁₆H₂₅NO₂
• Color and Shape: Off-White To Beige
• Molecular weight: 263.38

D,L N-desmethyl venlafaxine

CAS: 149289-30-5

D,L-N-desmethylvenlafaxine (D,LNDM) is a metabolite of venlafaxine that has been shown to have antidepressant properties …

• Formula: C₁₆H₂₅NO₂
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 263.38 g/mol