CAS 1496510-51-0: [(4aR)-1-(4-Fluorophenyl)-1,4,5,6,7,8-hexahydro-6-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl][4-(trifluoromethyl)-2-pyridinyl]methanone

Description: The chemical substance with the name "[(4aR)-1-(4-Fluorophenyl)-1,4,5,6,7,8-hexahydro-6-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl][4-(trifluoromethyl)-2-pyridinyl]methanone" and CAS number "1496510-51-0" is a complex organic compound characterized by its multi-cyclic structure and the presence of various functional groups. It features a hexahydroisoquinoline framework, which contributes to its potential biological activity. The presence of a fluorophenyl group and a trifluoromethyl-pyridine moiety suggests that it may exhibit significant lipophilicity, potentially influencing its pharmacokinetic properties. Additionally, the sulfonyl group attached to a pyrazole ring may enhance its reactivity and interaction with biological targets. This compound is likely to be of interest in medicinal chemistry, particularly for its potential therapeutic applications, although specific biological activities and mechanisms would require further investigation. Overall, its structural complexity and functional diversity make it a candidate for research in drug development and related fields.

Formula: C₂₇H₂₂F₄N₆O₃S

InChI: InChI=1S/C27H22F4N6O3S/c1-35-15-22(14-33-35)41(39,40)36-9-7-18-11-24-17(13-34-37(24)21-4-2-20(28)3-5-21)12-26(18,16-36)25(38)23-10-19(6-8-32-23)27(29,30)31/h2-6,8,10-11,13-15H,7,9,12,16H2,1H3/t26-/m0/s1

InChI key: InChIKey=WANIDIGFXJFFEL-SANMLTNESA-N

SMILES: O=C(C1=NC=CC(=C1)C(F)(F)F)C23C(=CC4=C(C=NN4C5=CC=C(F)C=C5)C2)CCN(C3)S(=O)(=O)C=6C=NN(C6)C

Synonyms:

• [(4aR)-1-(4-Fluorophenyl)-1,4,5,6,7,8-hexahydro-6-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl][4-(trifluoromethyl)-2-pyridinyl]methanone
• [(4aR)-1-(4-fluorophenyl)-6-(1-methyl-1H-pyrazole-4-sulfonyl)-1,4,5,6,7,8hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl][4-(trifluoromethyl)pyridin-2-yl]methanone
• Relacorilant
• Methanone, [(4aR)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-6-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl][4-(trifluoromethyl)-2-pyridinyl]-
• CORT 125134

Relacorilant

CAS: 1496510-51-0

Relacorilant is an oral glucocorticoid receptor antagonist with Ki of 7.2 nM, potential for treating …

• Formula: C₂₇H₂₂F₄N₆O₃S
• Purity: 98.53% - 99%
• Color and Shape: Solid
• Molecular weight: 586.56

Relacorilant

CAS: 1496510-51-0

Relacorilant is a drug that inhibits the production of epidermal growth factor (EGF). This drug …

• Formula: C₂₇H₂₂F₄N₆O₃S
• Purity: Min. 95%
• Molecular weight: 586.6 g/mol