CAS 153537-73-6: Plevitrexed

Formula: C₂₆H₂₅FN₈O₄

InChI: InChI=1S/C26H25FN8O4/c1-4-9-35(13-16-11-19-22(10-14(16)2)28-15(3)29-25(19)37)17-5-6-18(20(27)12-17)24(36)30-21(26(38)39)7-8-23-31-33-34-32-23/h1,5-6,10-12,21H,7-9,13H2,2-3H3,(H,30,36)(H,38,39)(H,28,29,37)(H,31,32,33,34)/t21-/m0/s1

InChI key: InChIKey=IEJSCSAMMLUINT-NRFANRHFSA-N

SMILES: O=C1N=C(NC=2C=C(C(=CC12)CN(C3=CC=C(C(=O)NC(C(=O)O)CCC4=NN=NN4)C(F)=C3)CC#C)C)C

Synonyms:

• (2S)-2-((4-(((2,7-Dimethyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl)(prop-2-ynyl)amino)-2-fluorobenzoyl)amino)-4-(1H-tetrazol-5-yl)butanoic acid
• (2S)-2-[(4-{[(2,7-dimethyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}-2-fluorobenzoyl)amino]-4-(2H-tetrazol-5-yl)butanoic acid
• (aS)-a-[[4-[[(1,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-2-fluorobenzoyl]amino]-1H-tetrazole-5-butanoic Acid
• 1H-Tetrazole-5-butanoic acid, α-[[4-[[(1,4-dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-2-fluorobenzoyl]amino]-, (S)-
• 1H-Tetrazole-5-butanoic acid, α-[[4-[[(1,4-dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-2-fluorobenzoyl]amino]-, (αS)-
• Bgc 9331
• Fluorobenzamido)-4-(1H-Tetrazol-5-Yl)Butyric Acid
• Nsc 696259
• Vamidex
• Zd 9331
• Plevitrexed

Plevitrexed

CAS: 153537-73-6

• Formula: C₂₆H₂₅FN₈O₄
• Color and Shape: Neat
• Molecular weight: 532.53

Plevitrexed

CAS: 153537-73-6

Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor & reduced folate carrier, …

• Formula: C₂₆H₂₅FN₈O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 532.53

Plevitrexed

CAS: 153537-73-6

Plevitrexed is a prodrug that is converted in the body to its active form, pemetrexed. …

• Formula: C₂₆H₂₅FN₈O₄
• Purity: Min. 95%
• Molecular weight: 532.53 g/mol