CAS 155229-76-8: (-)-3S,5R-FLUVASTATIN SODIUM SALT

Description: (-)-3S,5R-Fluvastatin sodium salt is a pharmaceutical compound primarily used as a cholesterol-lowering agent. It belongs to the class of statins, which function by inhibiting the enzyme HMG-CoA reductase, a key player in the biosynthesis of cholesterol in the liver. This compound is characterized by its chiral centers, which contribute to its specific stereochemistry, influencing its biological activity and efficacy. As a sodium salt, it is typically more soluble in water compared to its free acid form, enhancing its bioavailability. The compound exhibits a high affinity for the target enzyme, leading to a significant reduction in low-density lipoprotein (LDL) cholesterol levels in the bloodstream. Additionally, (-)-3S,5R-Fluvastatin sodium salt may possess anti-inflammatory properties and has been studied for potential benefits beyond cholesterol management, including cardiovascular protection. Its pharmacokinetics involve hepatic metabolism, and it is primarily excreted via bile. As with all medications, it is essential to consider potential side effects and interactions with other drugs when prescribing or using this compound.

Formula: C₂₄H₂₆FNO₄

InChI: InChI=1/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m0/s1

Synonyms:

• (3S,5R)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt
• (3S,5R,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, (3S,5R,6E)-

CAS: 155229-76-8

• Formula: C₂₄H₂₆FNO₄
• Molecular weight: 411.4659

(3S,5R)-Fluvastatin

CAS: 155229-76-8

Fluvastatin is a cholesterol-lowering drug that belongs to the group of statins. It has a …

• Formula: C₂₄H₂₆FNO₄
• Purity: Min. 95%
• Molecular weight: 411.47 g/mol