CAS 15717-45-0: Guanosine, 8-bromo-, 2′,3′,5′-triacetate

Description: Guanosine, 8-bromo-, 2′,3′,5′-triacetate is a modified nucleoside derivative of guanosine, characterized by the presence of a bromine atom at the 8-position of the purine base and three acetyl groups attached to the hydroxyl groups at the 2′, 3′, and 5′ positions of the ribose sugar. This compound is typically used in biochemical research and synthetic applications due to its structural modifications, which can influence its biological activity and interactions with nucleic acids. The presence of the bromine atom may enhance its reactivity or alter its binding properties compared to unmodified guanosine. The acetylation of the hydroxyl groups serves to increase the lipophilicity of the molecule, potentially facilitating its cellular uptake. As a nucleoside analog, it may also serve as a substrate or inhibitor in enzymatic reactions involving nucleotides. Overall, Guanosine, 8-bromo-, 2′,3′,5′-triacetate is a valuable compound in the study of nucleic acid chemistry and molecular biology.

Formula: C₁₆H₁₈BrN₅O₈

InChI: InChI=1S/C16H18BrN5O8/c1-5(23)27-4-8-10(28-6(2)24)11(29-7(3)25)14(30-8)22-12-9(19-15(22)17)13(26)21-16(18)20-12/h8,10-11,14H,4H2,1-3H3,(H3,18,20,21,26)/t8-,10-,11-,14-/m1/s1

InChI key: InChIKey=JLZCAXCVNVVXJL-IDTAVKCVSA-N

SMILES: O=C1N=C(N)NC2=C1N=C(Br)N2C3OC(COC(=O)C)C(OC(=O)C)C3OC(=O)C

Synonyms:

• 2',3',5'-tri-O-acetyl-8-bromoguanosine
• 2-amino-8-bromo-9-(2,3,5-tri-O-acetylpentofuranosyl)-3,9-dihydro-6H-purin-6-one
• 2′,3′,5′-Tri-O-acetyl-8-bromoguanosine
• 8-Bromo-2′,3′,5′-tri-O-acetylguanosine
• 8-Bromoguanosine 2',3',5'-triacetate
• 8-Bromoguanosine 2′,3′,5′-triacetate
• Guanosine, 8-bromo-, 2′,3′,5′-triacetate
• NSC 174056
• NSC 79210

Guanosine, 8-bromo-, 2',3',5'-triacetate

CAS: 15717-45-0

• Formula: C₁₆H₁₈BrN₅O₈
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 488.2468

2'',3'',5''-Tri-O-acetyl-8-bromoadenosine

CAS: 15717-45-0

• Formula: C₁₆H₁₈BrN₅O₈
• Molecular weight: 488.25

8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N

CAS: 15717-45-0

Applications 8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic …

• Formula: C₂C₁₄H₁₈BrNN₄O₈
• Color and Shape: Neat
• Molecular weight: 491.226

8-Bromo-2’,3’,5’-tri-O-acetylguanosine

CAS: 15717-45-0

Applications 8-Bromo-2’,3’,5’-tri-O-acetylguanosine (cas# 15717-45-0) is a compound useful in organic synthesis. References Kazmers, I.S., et …

• Formula: C₁₆H₁₈BrN₅O₈
• Color and Shape: Neat
• Molecular weight: 488.25

2',3',5'-Tri-O-acetyl-8-bromoguanosine

CAS: 15717-45-0

2',3',5'-Tri-O-acetyl-8-bromoguanosine is a synthetic nucleoside analog that inhibits the growth of tumor cells. It has …

• Formula: C₁₆H₁₈BrN₅O₈
• Purity: Min. 95%
• Color and Shape: Off-White To Light (Or Pale) Yellow Solid
• Molecular weight: 488.25 g/mol