CAS 158792-27-9: geninthiocin

Description:Geninthiocin, identified by its CAS number 158792-27-9, is a chemical compound that belongs to the class of thiopeptides, which are known for their unique structural features and biological activities. Thiopeptides typically contain a thiazole or thiazoline ring and exhibit potent antimicrobial properties, making them of interest in pharmaceutical research. Geninthiocin is characterized by its ability to inhibit bacterial protein synthesis, which contributes to its effectiveness against various bacterial strains. Its mechanism of action often involves binding to the ribosomal subunit, disrupting the translation process. Additionally, geninthiocin may exhibit low toxicity to mammalian cells, which is a desirable trait for potential therapeutic applications. The compound's stability, solubility, and bioavailability are also important characteristics that influence its efficacy as an antimicrobial agent. Ongoing research continues to explore its potential applications in treating infections and its role in the development of new antibiotics, particularly in the face of rising antibiotic resistance.

Formula:C₅₀H₄₉N₁₅O₁₅S

InChI:InChI=1/C50H49N15O15S/c1-12-27-48-61-30(16-79-48)41(72)54-21(5)39(70)65-35(50(10,11)77)45(76)57-23(7)47-64-33(25(9)80-47)44(75)55-20(4)38(69)56-22(6)46-60-29(15-78-46)34-26(49-62-31(17-81-49)42(73)63-32(24(8)66)43(74)59-27)13-14-28(58-34)40(71)53-19(3)37(68)52-18(2)36(51)67/h12-17,24,32,35,66,77H,2-7H2,1,8-11H3,(H2,51,67)(H,52,68)(H,53,71)(H,54,72)(H,55,75)(H,56,69)(H,57,76)(H,59,74)(H,63,73)(H,65,70)/b27-12+

Synonyms:
Sulfomycin I, 55-de(1-(aminocarbonyl)ethenyl)-22,24-deepithio-28-deethylidene-14-de(2-hydroxypropylidene)-21-demethoxy-17-demethyl-14-ethylidene-22,24,25,45-tetrahydro-24-hydroxy-24,24-dimethyl-21,28-bis(methylene)-22-oxo-