CAS 159414-99-0: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS 159414-99-0: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
Description:N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a complex nucleoside phosphoramidite used primarily in the synthesis of oligonucleotides. This compound features a modified cytidine base, which includes a fluorine atom at the 2' position, enhancing its stability and resistance to enzymatic degradation. The presence of the 4,4-dimethoxytrityl group at the 5' position serves as a protective group, facilitating the selective coupling during oligonucleotide synthesis. The N-acetyl group contributes to the solubility and stability of the molecule. Additionally, the 2-cyanoethyl-N,N-diisopropyl moiety at the 3' position is crucial for the formation of phosphodiester bonds, making it an essential component in the synthesis of DNA and RNA analogs. This compound is typically utilized in research and therapeutic applications, particularly in the development of antisense oligonucleotides and other nucleic acid-based technologies. Its unique structural features allow for enhanced performance in various biochemical applications.
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