CAS 16110-10-4: acetaminophen glucuronide

Description: Acetaminophen glucuronide, with the CAS number 16110-10-4, is a metabolite of acetaminophen (paracetamol) formed through the process of glucuronidation, which is a phase II metabolic reaction. This compound is characterized by its role in the detoxification and elimination of acetaminophen from the body. It is a conjugate formed when acetaminophen is linked to glucuronic acid, enhancing its solubility in water and facilitating excretion via urine. Acetaminophen glucuronide is typically non-toxic and is one of the primary metabolites found in human urine following acetaminophen ingestion. In terms of chemical structure, it contains a phenolic hydroxyl group and a glucuronic acid moiety, contributing to its polar characteristics. The compound is generally stable under physiological conditions but can be influenced by various factors, including liver function and the presence of other substances that may affect glucuronidation pathways. Understanding its properties is crucial for assessing the pharmacokinetics and potential toxicity of acetaminophen, especially in cases of overdose.

Formula: C₁₄H₁₇NO₈

InChI: InChI=1S/C14H17NO8/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21)/t9-,10-,11+,12-,14+/m0/s1

InChI key: InChIKey=IPROLSVTVHAQLE-BYNIDDHOSA-N

SMILES: O=C(O)C1OC(OC2=CC=C(C=C2)NC(=O)C)C(O)C(O)C1O

Synonyms:

• 4-(Acetylamino)phenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 4-(acetylamino)phenyl beta-D-glucopyranosiduronic acid
• 4-Glucuronosidoacetanilide
• 4-Hydroxyacetanilide glucuronide
• Acetanilide glucuronide
• Deethylphenacetin glucuronide
• Glucopyranosiduronic acid, p-acetamidophenyl, β-<span class="text-smallcaps">D</span>-
• N-Acetyl-4-aminophenol glucuronide
• N-Acetyl-4-glucuronosidoaniline
• N-Acetyl-p-aminophenyl glucuronide
• Paracetamol O-glucuronide
• Paracetamol glucuronide
• Paracetamol β-glucuronide
• Pcm-G
• beta-D-Glucopyranosiduronic acid, 4-(acetylamino)phenyl
• p-Acetamidophenyl <span class="text-smallcaps">D</span>-glucosiduronic acid
• p-Acetamidophenyl glucosiduronic acid
• p-Acetamidophenyl glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-(acetylamino)phenyl
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, p-acetamidophenyl
• β-<span class="text-smallcaps">D</span>-Glucosiduronic acid, p-acetamidophenyl

acetaminophen glucuronide

CAS: 16110-10-4

• Formula: C₁₄H₁₇NO₈
• Molecular weight: 327.2867

Acetaminophen β-D-glucuronide

CAS: 16110-10-4

• Formula: C₁₄H₁₇NO₈
• Purity: 95% min
• Color and Shape: white crystalline solid
• Molecular weight: 327.29g/mol

Acetaminophen D-glucuronide

CAS: 16110-10-4

• Formula: C₁₄H₁₇NO₈
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 327.29

Acetaminophen D-glucuronide

CAS: 16110-10-4

Acetaminophen D-glucuronide (APG) is a metabolite of acetaminophen. It is a major metabolite produced by …

• Formula: C₁₄H₁₇NO₈
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 327.29 g/mol