Description:Fmoc-Met(O2)-OH, also known as Fmoc-protected methionine with a sulfoxide modification, is a chemical compound commonly used in peptide synthesis and research. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The methionine residue is modified with a sulfoxide (O2) group, which can influence the compound's reactivity and properties, such as solubility and stability. This modification can also affect the biological activity of peptides synthesized with this amino acid. Fmoc-Met(O2)-OH is typically soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), making it suitable for various synthetic applications. Its use is prevalent in the field of medicinal chemistry and biochemistry, particularly in the development of peptide-based therapeutics. As with many chemical substances, proper handling and storage conditions are essential to maintain its integrity and effectiveness in laboratory settings.
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