CAS 16543-55-8: N-Nitrosonornicotine

Description: N-Nitrosonornicotine (CAS 16543-55-8) is a nitrosamine derivative of the tobacco alkaloid nornicotine. It is characterized by its molecular structure, which includes a nitroso group (-N=O) attached to the nornicotine backbone. This compound is of significant interest in toxicology and cancer research due to its potential carcinogenic properties, particularly in relation to tobacco use. N-Nitrosonornicotine is known to exhibit mutagenic effects, which can lead to DNA damage and contribute to the development of various cancers. It is typically found in tobacco products and is formed during the curing and processing of tobacco leaves. The substance is a colorless to pale yellow liquid and is soluble in organic solvents. Its stability can be influenced by environmental factors such as temperature and pH. Due to its toxicological implications, N-nitrosonornicotine is subject to regulatory scrutiny, and research continues to explore its mechanisms of action and effects on human health.

Formula: C₉H₁₁N₃O

InChI: InChI=1S/C9H11N3O/c13-11-12-6-2-4-9(12)8-3-1-5-10-7-8/h1,3,5,7,9H,2,4,6H2/t9-/m0/s1

InChI key: InChIKey=XKABJYQDMJTNGQ-VIFPVBQESA-N

SMILES: O=NN1CCCC1C=2C=NC=CC2

Synonyms:

• (S)-N′-Nitrosonornicotine
• 1-Nitroso-2-(3-Pyridyl)Pyrrolidine
• 1’-Demethyl-1’-Nitroso-Nicotin
• 1’-Desmethyl-1’-Nitrosonicotine
• 1’-Nitroso-1’-Demethyl-Nicotin
• 1’-Nitroso-1’-Demethylnicotine
• 1’-Nitrosonornicotine
• 3-(1-Nitrosopyrrolidin-2-Yl)Pyridine
• 3-[(2S)-1-Nitroso-2-pyrrolidinyl]pyridine
• 3-[(2S)-1-Nitrosopyrrolidin-2-yl]pyridine
• NNN
• Nicotine, 1′-demethyl-1′-nitroso-
• Nitrosonornicotine
• Nornicotine, N-nitroso-
• Pyridine, 3-(1-nitroso-2-pyrrolidinyl)-, (S)-
• Pyridine, 3-[(2S)-1-nitroso-2-pyrrolidinyl]-
• anti-N′-Nitrosonornicotine
• syn-N′-Nitrosonornicotine

N'-Nitrosonornicotine

CAS: 16543-55-8

• Formula: C₉H₁₁N₃O
• Color and Shape: Neat
• Molecular weight: 177.20

(2S)-N'-Nitrosonornicotine

CAS: 16543-55-8

Stability Hygroscopic Applications A tobacco alkaloid as risk factor of human cancer. Not a dangerous …

• Formula: C₉H₁₁N₃O
• Color and Shape: Light Yellow
• Molecular weight: 177.20

(2S)-N’-Nitrosonornicotine

CAS: 16543-55-8

(2S)-N’-Nitrosonornicotine is a tobacco-specific nitrosamine that has been shown to be carcinogenic in the experimental …

• Formula: C₉H₁₁N₃O
• Purity: Min. 95%
• Color and Shape: Beige Slightly Yellow Powder
• Molecular weight: 177.2 g/mol

N-Nitrosonornicotine

CAS: 16543-55-8

N-Nitrosonornicotine, a tobacco-specific nitrosamine, exhibits carcinogenic and mutagenic properties, and is capable of inducing micronuclei …

• Formula: C₉H₁₁N₃O
• Color and Shape: Liquid
• Molecular weight: 177.2