Description:Fmoc-D-Cys(Trt)-OH, with the CAS number 167015-11-4, is a protected amino acid derivative commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective moiety for the amino group, allowing for selective reactions during peptide assembly. The "D-Cys" indicates that the cysteine residue is in its D-enantiomer form, which is significant for the stereochemistry of peptides. The "Trt" (trityl) group protects the thiol side chain of cysteine, preventing unwanted reactions during synthesis. This compound is typically utilized in solid-phase peptide synthesis, where the protection of functional groups is crucial for the successful formation of peptide bonds. Fmoc-D-Cys(Trt)-OH is soluble in organic solvents, and its stability under standard peptide coupling conditions makes it a valuable building block in the development of peptides and proteins for research and therapeutic applications. Its unique characteristics allow for the incorporation of cysteine into peptides, which can be important for disulfide bond formation and overall structural integrity.
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