CAS: 1680184-59-1 - (2Z)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide

Formula: C₂₄H₂₅ClFN₅O₃

InChI: InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3-/t16-/m0/s1

InChI key: InChIKey=ULXXDDBFHOBEHA-QGZUEGPWSA-N

SMILES: O=C(C=CCN(C)C)NC1=CC=2C(=NC=NC2NC3=CC=C(F)C(Cl)=C3)C=C1OC4COCC4

Synonyms:

• (2Z)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
• 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2Z)-

Afatinib Impurity D (Z-Afatinib)

CAS: 1680184-59-1

• Formula: C₂₄H₂₅ClFN₅O₃
• Molecular weight: 485.95

(2Z)-Afatinib

CAS: 1680184-59-1

• Formula: C₂₄H₂₅ClFN₅O₃
• Color and Shape: Neat
• Molecular weight: 485.94

(2Z)-Afatinib

CAS: 1680184-59-1

Afatinib is a potent, selective, and ATP-competitive inhibitor of EGFR. It blocks the phosphorylation of …

• Formula: C₂₄H₂₅ClFN₅O₃
• Purity: Min. 95%
• Molecular weight: 485.9 g/mol