CAS 168834-43-3: Benzenemethanol, 2-amino-5-chloro-.alpha.-(2-cyclopropylethynyl)-.alpha.-(trifluoromethyl)-
CAS 168834-43-3: Benzenemethanol, 2-amino-5-chloro-.alpha.-(2-cyclopropylethynyl)-.alpha.-(trifluoromethyl)-
Description:Benzenemethanol, 2-amino-5-chloro-.alpha.-(2-cyclopropylethynyl)-.alpha.-(trifluoromethyl)-, identified by its CAS number 168834-43-3, is a chemical compound characterized by its complex structure, which includes a benzene ring, an amino group, and a trifluoromethyl group. The presence of the cyclopropylethynyl moiety contributes to its unique reactivity and potential applications in medicinal chemistry. This compound is likely to exhibit properties typical of aromatic amines, such as moderate solubility in organic solvents and potential biological activity. The chloro and trifluoromethyl substituents can influence its electronic properties, potentially enhancing its lipophilicity and altering its interaction with biological targets. As with many compounds containing halogens and functional groups, it may also exhibit specific reactivity patterns, making it of interest in synthetic organic chemistry and drug development. Safety and handling precautions are essential due to the presence of halogenated groups, which may pose environmental and health risks.
Applications 2-Amino-5-chloro-α-(cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol-d4 is an isotope labelled impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase …
Applications 2-Amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol is an impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. References …
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