CAS 16937-99-8: tert-Butoxycarbonyl-D-leucine
Description:Tert-Butoxycarbonyl-D-leucine, commonly abbreviated as Boc-D-leucine, is a derivative of the amino acid leucine, characterized by the presence of a tert-butoxycarbonyl (Boc) protecting group. This compound is typically utilized in peptide synthesis as a protective group for the amino functionality, which helps to prevent unwanted reactions during the synthesis process. The Boc group is known for its stability under basic conditions and can be easily removed under acidic conditions, making it a popular choice in organic synthesis. Tert-Butoxycarbonyl-D-leucine is a white to off-white solid, and its molecular structure includes a branched aliphatic side chain, characteristic of leucine, which contributes to its hydrophobic properties. The compound is soluble in organic solvents such as dichloromethane and dimethylformamide but has limited solubility in water. Its applications extend beyond peptide synthesis to include studies in biochemistry and medicinal chemistry, where it serves as a building block for various bioactive compounds.
Formula:C11H21NO4
InChI:InChI=1S/C11H21NO4/c1-7(2)6-8(9(13)14)12-10(15)16-11(3,4)5/h7-8H,6H2,1-5H3,(H,12,15)(H,13,14)/t8-/m1/s1
InChI key:InChIKey=MDXGYYOJGPFFJL-MRVPVSSYSA-N
SMILES:O=C(OC(C)(C)C)NC(C(=O)O)CC(C)C
- Synonyms:
- (2R)-2-[[(tert-Butoxy)carbonyl]amino]-4-methylpentanoic acid
- (2R)-4-Methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
- (R)-2-(tert-Butoxycarbonylamino)-4-methylpentanoic acid
- (R)-2-[[tert-Butoxycarbonyl)amino]-4-methylpentanoicacid
- (R)-N-(t-Butoxycarbonyl)leucine
- <span class="text-smallcaps">D</span>-Boc leucine
- <span class="text-smallcaps">D</span>-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
- Boc-D-Leu-OH hydrate
- Boc-D-Leu-OH.H2O
- Boc-D-Leu-Oh
- See more synonyms
- Boc-D-Leucine
- L-Leucine-5,5,5-D3, N-T-Boc Deriv.H20
- Leucine, N-carboxy-, N-tert-butyl ester, <span class="text-smallcaps">D</span>-
- N-(Tert-Butoxycarbonyl)-D-Leucine
- N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">D</span>-leucine
- N-(tert-butoxycarbonyl)-D-leucine hydrate
- N-Alpha-T-Boc-D-Leucine
- N-Boc-<span class="text-smallcaps">D</span>-leucine
- N-Boc-D-Leu-OH monohydrate
- N-T-Boc-D-Leucine
- N-Tert-Butoxycarbonyl-D-Leucine 1-Hydrate
- N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">D</span>-leucine
- tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-leucine
- Leucine, N-carboxy-, N-tert-butyl ester, D-
- N-[(1,1-Dimethylethoxy)carbonyl]-D-leucine
- D-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
- tert-Butoxycarbonyl-D-leucine