CAS 1738-86-9: Z-glycine 4-nitrophenyl ester

Description: Z-glycine 4-nitrophenyl ester, also known as Z-Gly-ONp, is a chemical compound characterized by its structure, which includes a glycine moiety protected by a benzyloxycarbonyl (Z) group and an ester formed with 4-nitrophenol. This compound is typically used in peptide synthesis as an intermediate due to its ability to facilitate the formation of peptide bonds. The Z group serves as a protective group that can be removed under specific conditions, allowing for the selective deprotection of the amino acid. The presence of the 4-nitrophenyl ester enhances the reactivity of the carboxylic acid component, making it a useful building block in organic synthesis. Z-glycine 4-nitrophenyl ester is generally stable under standard laboratory conditions but should be handled with care due to the potential reactivity of the nitrophenyl group. Its applications extend to biochemistry and medicinal chemistry, particularly in the development of peptide-based drugs and research into enzyme mechanisms.

Formula: C₁₆H₁₄N₂O₆

InChI: InChI=1S/C16H14N2O6/c19-15(24-14-8-6-13(7-9-14)18(21)22)10-17-16(20)23-11-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,20)

InChI key: InChIKey=LHFNPUGRSYOPLF-UHFFFAOYSA-N

SMILES: O=C(OCC=1C=CC=CC1)NCC(=O)OC2=CC=C(C=C2)N(=O)=O

Synonyms:

• (4-Nitrophenyl) 2-(phenylmethoxycarbonylamino)acetate
• 4-nitrophenyl N-[(benzyloxy)carbonyl]glycinate
• Benzyloxycarbonylglycine p-nitrophenyl ester
• Carbobenzoxyglycine p-nitrophenyl ester
• Glycine, N-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester
• Glycine, N-carboxy-, N-benzyl p-nitrophenyl ester
• N-(Benzyloxycarbonyl)glycine 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)glycine p-nitrophenyl ester
• N-CBZ-Glycine p-nitrophenyl ester N-Carbobenzyloxy-glycine p-nitrophenyl ester
• N-Carbobenzoxyglycine 4-Nitrophenyl ester
• N-Carbobenzoxyglycine-p-nitrophenyl ester
• N-Carboxyglycine N-benzyl p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]glycine 4-nitrophenyl ester
• N-α-Carbobenzoxyglycine p-nitrophenyl ester
• NSC 405051
• Z-Gly-ONp
• p-Nitrophenyl (N-carbobenzoxy)glycinate
• p-Nitrophenyl N-(benzyloxycarbonyl)aminoacetate
• p-Nitrophenyl N-benzyloxycarbonylglycinate
• p-Nitrophenyl Z-glycinate
• p-Nitrophenyl benzyloxycarbonylglycinate
• p-Nitrophenyl carbobenzoxyglycinate

N-Benzyloxycarbonylglycine 4-Nitrophenyl Ester

CAS: 1738-86-9

• Formula: C₁₆H₁₄N₂O₆
• Purity: >98.0%(HPLC)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 330.30

Z-Gly-ONP

CAS: 1738-86-9

• Formula: C₁₆H₁₄N₂O₆
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 330.2922

4-Nitrophenyl ((Benzyloxy)Carbonyl)Glycinate

CAS: 1738-86-9

• Purity: 95%
• Molecular weight: 330.29g/mol

4-Nitrophenyl 2-(((benzyloxy)carbonyl)amino)acetate

CAS: 1738-86-9

• Purity: 95.0%
• Color and Shape: Solid, White to off-white powder
• Molecular weight: 330.2959899902344

N-Cbz-glycine 4-nitrophenyl ester

CAS: 1738-86-9

N-Cbz-glycine 4-nitrophenyl ester is a substrate for serine proteases. It is used to study the …

• Formula: C₁₆H₁₄N₂O₆
• Purity: Min. 95%
• Molecular weight: 330.29 g/mol