CAS: 182431-12-5 - Lomitapide

Formula: C₃₉H₃₇F₆N₃O₂

InChI: InChI=1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-17-27(18-16-26)39(43,44)45/h1-6,9-18,28H,7-8,19-25H2,(H,46,50)(H,47,49)

InChI key: InChIKey=MBBCVAKAJPKAKM-UHFFFAOYSA-N

SMILES: O=C(NC1CCN(CCCCC2(C(=O)NCC(F)(F)F)C=3C=CC=CC3C=4C=CC=CC42)CC1)C=5C=CC=CC5C=6C=CC(=CC6)C(F)(F)F

Synonyms:

• 9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4′-(trifluoromethyl)[1,1′-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-
• Aegr 733
• Bms 201038
• Bms 201038-01
• Bms 201238
• Lojuxta
• Lomitapide
• N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4′-(trifluoromethyl)[1,1′-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide

Lomitapide

CAS: 182431-12-5

• Formula: C₃₉H₃₇F₆N₃O₂
• Purity: >98.0%(HPLC)(qNMR)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 693.73

9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-

CAS: 182431-12-5

• Formula: C₃₉H₃₇F₆N₃O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 693.7204

Lomitapide

CAS: 182431-12-5

• Formula: C₃₉H₃₇F₆N₃O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 693.73

Lomitapide-d8

CAS: 182431-12-52459377-96-7

• Formula: C₃₉H₂₉D₈F₆N₃O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 701.78

Lomitapide

CAS: 182431-12-5

Lomitapide (AEGR-733) blocks MTP, a key enzyme in dietary lipid absorption and VLDL assembly.

• Formula: C₃₉H₃₇F₆N₃O₂
• Purity: 99.23% - 99.77%
• Color and Shape: Solid
• Molecular weight: 693.72

Lomitapide

CAS: 182431-12-5

Applications Lomitapide is a drug used in the treatment of obesity and aids in lowering …

• Formula: C₃₉H₃₇F₆N₃O₂
• Color and Shape: Neat
• Molecular weight: 693.7204

Lomitapide-d8

CAS: 182431-12-5

• Formula: C₃₉D₈H₂₉F₆N₃O₂
• Color and Shape: Neat
• Molecular weight: 701.77

N-(2,2,2-Trifluoroethyl)-9-(4-[4-[4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamido]piperidin-1-yl]butyl)-9H-fluorene-9-carboxamide

CAS: 182431-12-5

Lomitapide is a drug that inhibits the enzyme PCSK9, which regulates the amount of low-density …

• Formula: C₃₉H₃₇F₆N₃O₂
• Purity: Min. 95%
• Molecular weight: 693.72 g/mol