CAS: 183133-96-2 - [2aR[2aalpha,4beta,4abeta,6beta,9alpha(2R,3S),11beta,12alpha,12aalpha,12balpha]]-12b-Acetoxy-9-[3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionyloxy]-12-(benzoyloxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d

Formula: C₄₅H₅₇NO₁₄

InChI: InChI=1S/C45H57NO14/c1-24-28(57-39(51)33(48)32(26-17-13-11-14-18-26)46-40(52)60-41(3,4)5)22-45(53)37(58-38(50)27-19-15-12-16-20-27)35-43(8,36(49)34(55-10)31(24)42(45,6)7)29(54-9)21-30-44(35,23-56-30)59-25(2)47/h11-20,28-30,32-35,37,48,53H,21-23H2,1-10H3,(H,46,52)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1

InChI key: InChIKey=BMQGVNUXMIRLCK-OAGWZNDDSA-N

SMILES: O=C(OC(C)(C)C)NC(C=1C=CC=CC1)C(O)C(=O)OC2C(=C3C(OC)C(=O)C4(C)C(OC)CC5OCC5(OC(=O)C)C4C(OC(=O)C=6C=CC=CC6)C(O)(C2)C3(C)C)C

Synonyms:

• 3'-(tert-Butoxycarbonylamino)-10-O-deacetyl-3'-debenzamido-7,10-O-dimethylpaclitaxel
• Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
• Cabazitaxel
• DEP cabazitaxel
• Jevtana
• Rpr-116258A
• Tax-258
• Txd-258
• Xrp-6258

Cabazitaxel

CAS: 183133-96-2

• Formula: C₄₅H₅₇NO₁₄
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 835.94

Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

CAS: 183133-96-2

• Formula: C₄₅H₅₇NO₁₄
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 835.9324

Cabazitaxel-d9

CAS: 1383572-19-7 183133-96-2

• Formula: C₄₅H₄₈D₉NO₁₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 845.00

Cabazitaxel

CAS: 183133-96-2

• Formula: C₄₅H₅₇NO₁₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 835.94

Cabazitaxel

CAS: 183133-96-2

• Formula: C₄₅H₅₇NO₁₄
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 835.94

Cabazitaxel

CAS: 183133-96-2

• Formula: C₄₅H₅₇NO₁₄
• Purity: 95%~99%
• Molecular weight: 835.944

Cabazitaxel

CAS: 183133-96-2

• Formula: C₄₅H₅₇NO₁₄
• Color and Shape: Neat
• Molecular weight: 835.93

Cabazitaxel Impurity 2

CAS: 1383572-19-7 183133-96-2

• Formula: C₃₂H₄₂O₁₀
• Color and Shape: White To Off-White Solid
• Molecular weight: 586.69

Cabazitaxel

CAS: 183133-96-2

Cabazitaxel (XRP6258) is a taxane used for castration-resistant metastatic prostate cancer post-docetaxel failure.

• Formula: C₄₅H₅₇NO₁₄
• Purity: 96.81% - ≥95%
• Color and Shape: Solid
• Molecular weight: 835.93

Cabazitaxel

CAS: 183133-96-2

Applications A novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate …

• Formula: C₄₅H₅₇NO₁₄
• Color and Shape: White Solid
• Molecular weight: 835.93

Cabazitaxel

CAS: 183133-96-2

Inhibitor of tubulin depolymerization; anti-neoplastic

• Formula: C₄₅H₅₇NO₁₄
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 835.93 g/mol