CAS 184866-29-3: (S)-Lercanidipine Hydrochloride

Description: (S)-Lercanidipine Hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension. It belongs to the dihydropyridine class of compounds, which are characterized by their ability to selectively inhibit calcium influx through L-type calcium channels in vascular smooth muscle and cardiac tissue. This action leads to vasodilation and a subsequent reduction in blood pressure. The substance is a chiral molecule, with the (S)-enantiomer being the active form that exhibits greater pharmacological activity. Lercanidipine is known for its long half-life, allowing for once-daily dosing, which enhances patient compliance. In addition to its antihypertensive effects, it may also have beneficial effects on endothelial function. The hydrochloride salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. Common side effects may include peripheral edema, headache, and flushing, though it is generally well-tolerated. As with any medication, it is important to consider contraindications and potential drug interactions when prescribing Lercanidipine.

Formula: C₃₆H₄₂ClN₃O₆

InChI: InChI=1/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H/t33-;/m0./s1

Synonyms:

• (4S)-1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride
• 2-[(3,3-diphenylpropyl)(methyl)amino]-1,1-dimethylethyl methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride

(S)-Lercanidipine-13C-d3 HCl

CAS: 184866-29-3

• Formula: C₃₅₁₃CH₃₈D₃N₃O₆·HCl
• Color and Shape: Yellow Solid
• Molecular weight: 615.75 36.46

(S)-Lercanidipine HCl

CAS: 184866-29-3

• Formula: C₃₆H₄₁N₃O₆·HCl
• Color and Shape: Yellow Solid
• Molecular weight: 611.74 36.46

(S)-Lercanidipine Hydrochloride

CAS: 184866-29-3

• Formula: C₃₆H₄₁N₃O₆·ClH
• Color and Shape: Neat
• Molecular weight: 648.19

(S)-Lercanidipine hydrochloride

CAS: 184866-29-3

(S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-lercanidipine hydrochloride is a potent blocker of …

• Formula: C₃₆H₄₂ClN₃O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 648.19

(S)-Lercanidipine hydrochloride

CAS: 184866-29-3

Please enquire for more information about (S)-Lercanidipine hydrochloride including the price, delivery time and more …

• Formula: C₃₆H₄₂ClN₃O₆
• Purity: Min. 95%
• Molecular weight: 648.19 g/mol