CAS 1880-61-1: 17-OXODEXAMETHASONE
Description:17-Oxodexamethasone, with the CAS number 1880-61-1, is a synthetic glucocorticoid and a derivative of dexamethasone, which is a potent anti-inflammatory and immunosuppressive agent. This compound is characterized by its steroidal structure, featuring a cyclopentanoperhydrophenanthrene core, which is typical of corticosteroids. It possesses a ketone functional group at the 17-position, which distinguishes it from its parent compound, dexamethasone. 17-Oxodexamethasone exhibits anti-inflammatory properties by inhibiting the release of inflammatory mediators and modulating immune responses. It is often studied for its potential therapeutic applications in conditions such as autoimmune diseases, allergies, and certain types of cancer. The compound is typically administered in various formulations, including oral and injectable forms, and its pharmacokinetics involve metabolism primarily in the liver. As with other glucocorticoids, its use may be associated with side effects, particularly with long-term administration, necessitating careful monitoring and dosage adjustments.
Formula:C20H25FO3
InChI:InChI=1/C20H25FO3/c1-11-8-15-14-5-4-12-9-13(22)6-7-19(12,3)20(14,21)16(23)10-18(15,2)17(11)24/h6-7,9,11,14-16,23H,4-5,8,10H2,1-3H3
- Synonyms:
- 9-Fluoro-11b-hydroxy-16a-methyl Androsta-1,4-diene-3,17-dione
- Nsc 50909
- 9-Fluoro-11-hydroxy-16-methyl-(11b,16a ) Androsta-1,4-diene-3,17-dione
- 9alpha-Fluoro-11beta-hydroxy-16alpha-methyl-1,4-androstadiene-3,17-dio ne
- 9-Fluoro-11-hydroxy-16a-methyl Androsta-1,4-diene-3,17-dione
- 9-Fluoro-11-hydroxy-16-methyl-(11,16a ) Androsta-1,4-diene-3,17-dione
- (11Beta,16Alpha)-9-Fluoro-11-Hydroxy-16-Methylandrosta-1,4-Diene-3,17-Dione
- 9-Fluoro-11-Hydroxy-16-Methylandrosta-1,4-Diene-3,17-Dione
