CAS 1882-82-2: 21-Deoxycortisone
Description:21-Deoxycortisone, also known as 21-deoxycorticosterone, is a steroid hormone that is classified as a mineralocorticoid. It is a derivative of corticosterone and is primarily involved in the regulation of electrolyte and water balance in the body. The chemical structure of 21-deoxycortisone features a steroid backbone with specific functional groups that influence its biological activity. It is characterized by the absence of a hydroxyl group at the C21 position, which distinguishes it from its parent compound, corticosterone. This modification affects its affinity for mineralocorticoid receptors and its overall physiological effects. 21-Deoxycortisone is synthesized in the adrenal cortex and plays a role in the renin-angiotensin-aldosterone system, impacting blood pressure and fluid balance. In clinical settings, it may be studied for its potential effects on conditions related to adrenal insufficiency or hypertension. As with many steroid hormones, its activity can be influenced by various factors, including enzymatic conversion and receptor interactions.
Formula:C21H28O4
InChI:InChI=1S/C21H28O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h10,15-16,18,25H,4-9,11H2,1-3H3/t15-,16-,18+,19-,20-,21-/m0/s1
InChI key:InChIKey=PUKLDDOGISCFCP-JSQCKWNTSA-N
SMILES:O=C1C=C2CCC3C(C(=O)CC4(C)C3CCC4(O)C(=O)C)C2(C)CC1
- Synonyms:
- 17-Alpha-Hydroxypregn-4-Ene-3,11,20-Trione
- 17-Hydroxypregn-4-Ene-3,11,20-Trione
- 17α-Hydroxy-11-oxoprogesterone
- 17α-Hydroxypregn-4-ene-3,11,20-trione
- 21-Deoxycortisone
- 21-Desoxycortisone
- 4-Pregnene-17α-ol-3,11,20-trione
- 6-Pregn-4-en-17α-ol-3,11,20-trione
- NSC 38722
- Pregn-4-ene-3,11,20-trione, 17-hydroxy-
- See more synonyms
