CAS 189028-93-1: Ezetimibe Intermediate

Description: Ezetimibe Intermediate, with the CAS number 189028-93-1, is a chemical compound that serves as a precursor in the synthesis of the cholesterol absorption inhibitor ezetimibe. This intermediate typically exhibits characteristics common to organic compounds, including a specific molecular structure that facilitates its role in pharmaceutical applications. It is likely to be a solid at room temperature, with moderate solubility in organic solvents, which is typical for many intermediates used in drug synthesis. The compound may contain functional groups that are reactive, allowing for further chemical transformations necessary to produce the final active pharmaceutical ingredient. Safety data sheets would indicate handling precautions, as intermediates can often be hazardous. Overall, Ezetimibe Intermediate plays a crucial role in the production of ezetimibe, which is used to lower cholesterol levels by inhibiting the absorption of cholesterol in the intestines.

Formula: C₂₀H₁₈FNO₄

InChI: InChI=1S/C20H18FNO4/c21-16-11-9-15(10-12-16)18(23)7-4-8-19(24)22-17(13-26-20(22)25)14-5-2-1-3-6-14/h1-3,5-6,9-12,17H,4,7-8,13H2/t17-/m1/s1

InChI key: InChIKey=XXSSRSVXDNUAQX-QGZVFWFLSA-N

SMILES: O=C1OCC(C=2C=CC=CC2)N1C(=O)CCCC(=O)C3=CC=C(F)C=C3

Synonyms:

• (4S)-3-[5-(4-Fluorophenyl)-1,5-Dioxopenyl]-4-Phenyl-2-Oxazolidinone
• (4S)-3-[5-(4-Fluorophenyl)-1,5-dixopenyl]-4-phenyl-2-oxazolidinone
• (4S)-3-[5-(4-fluorophenyl)1,5-dioxophentyl]-4-phenyl-2-oxazolidinone
• (4S)-4-Phenyl-3-[5-(4-fluorophenyl)-5-oxopentanoyl]-1,3-oxazolidin-2-one
• (S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl) pentane-1,5-dione
• (S)-3-(5-(4-fluorophenyl)-5-oxopentanoyl)-4-phenyloxazolidin-2-one
• (S)-3-[4-(4-Fluorobenzoyl)-1-oxobutyl]-4-phenyloxazolidin-2-one
• (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one
• 1,5-Pentanedione, 1-(4-fluorophenyl)-5-[(4S)-2-oxo-4-phenyl-3-oxazolidinyl]-
• 1-(4-Fluorophenyl)-5-[(4S)-2-oxo-4-phenyl-3-oxazolidinyl]-1,5-pentanedione
• 1-(4-fluorophenyl)-5-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]pentane-1,5-dione
• 2-Oxazolidinone, 3-[5-(4-Fluorophenyl)-1,5-Dioxopentyl]-4-Phenyl-, (4S)-
• 2-Oxazolidinone, 3-[5-(4-fluorophenyl)-1,5-dioxopentyl]-4-phenyl-, (4S)-(Intermediate of Ezetimibe)
• 2-Oxazolidinone, 3-[5-(4-fluorophenyl)-1,5-dioxopentyl]-4-phenyl-, (S)-
• 2-Oxazolidinone,3-[5-(4-Fluorophenyl)-1,5-Dioxopentyl]-4-Phenyl
• 3-[5-(4-Fluorophenyl)-1,5-Dixopenyl]-4-Phenyl-(4s)-2-Oxazolidinone
• 3-[5-(4-fluorophenyl)-1,5-dioxopentyl]-4-phenyl-(4S)-2-oxazolidinone
• 3-[5-[(4-Fluorophenyl)-1-5-Dioxopenta]-Yl-4-(S)-Phenyl Oxnzolidine-2-One
• API`sIntermediate
• Zt-4

(S)-4-Phenyl-3-[5-(4-fluorophenyl)-5-oxopentanoyl]-2-oxazolidinone

CAS: 189028-93-1

• Formula: C₂₀H₁₈FNO₄
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 355.37

1,5-Pentanedione, 1-(4-fluorophenyl)-5-[(4S)-2-oxo-4-phenyl-3-oxazolidinyl]-

CAS: 189028-93-1

• Formula: C₂₀H₁₈FNO₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 355.3596

Ezetimibe Impurity 8

CAS: 189028-93-1

• Formula: C₂₀H₁₈FNO₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 355.37

1-(4-FluoroPhenyl)-5-[(4S)-2-Oxo-4-Phenyl-1,3-Oxazolidin-3-yl]Pentane-1,5-Dione

CAS: 189028-93-1

• Purity: 99%+
• Molecular weight: 355.36g/mol

(S)-1-(4-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione

CAS: 189028-93-1

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 355.364990234375

3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4(S)-phenyl-2-oxazolidinone

CAS: 189028-93-1

• Formula: C₂₀H₁₈FNO₄
• Color and Shape: Neat
• Molecular weight: 355.3596

3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4S-phenyl-2-oxazolidinone

CAS: 189028-93-1

Ezetimibe is a drug that is used for the treatment of high cholesterol. It inhibits …

• Formula: C₂₀H₁₈FNO₄
• Purity: Min. 95%
• Molecular weight: 355.36 g/mol