CAS 198821-22-6: Merimepodib

Description: Merimepodib is a chemical compound known for its role as an antiviral agent, particularly in the context of research related to viral infections. It functions primarily as a selective inhibitor of the enzyme inosine monophosphate dehydrogenase (IMPDH), which is crucial for the de novo synthesis of purine nucleotides. By inhibiting this enzyme, Merimepodib disrupts the replication of certain viruses, making it a candidate for therapeutic applications against viral diseases. The compound has shown potential in preclinical studies, particularly against viruses such as hepatitis C and other RNA viruses. In terms of its chemical properties, Merimepodib is characterized by its specific molecular structure, which includes functional groups that contribute to its biological activity. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are important factors in determining its efficacy and safety profile in clinical settings. As research continues, Merimepodib may offer insights into novel antiviral strategies and contribute to the development of effective treatments for viral infections.

Formula: C₂₃H₂₄N₄O₆

InChI: InChI=1S/C23H24N4O6/c1-30-20-10-17(5-6-19(20)21-12-24-14-32-21)27-22(28)26-16-4-2-3-15(9-16)11-25-23(29)33-18-7-8-31-13-18/h2-6,9-10,12,14,18H,7-8,11,13H2,1H3,(H,25,29)(H2,26,27,28)/t18-/m0/s1

InChI key: InChIKey=JBPUGFODGPKTDW-SFHVURJKSA-N

SMILES: O=C(OC1COCC1)NCC=2C=CC=C(C2)NC(=O)NC=3C=CC(C=4OC=NC4)=C(OC)C3

Synonyms:

• (3S)-tetrahydrofuran-3-yl [3-({[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoyl}amino)benzyl]carbamate
• Carbamic acid, N-[[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl ester
• Carbamic acid, [[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl ester
• Carbamic acid, [[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, tetrahydro-3-furanyl ester, (S)-
• Merimepodib
• Vi-21497
• Vx-497

Carbamic acid, N-[[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl ester

CAS: 198821-22-6

• Formula: C₂₃H₂₄N₄O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 452.4599

Merimepodib

CAS: 198821-22-6

Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).

• Formula: C₂₃H₂₄N₄O₆
• Purity: 98.77% - 99.31%
• Color and Shape: Solid
• Molecular weight: 452.46

Carbamic acid, N-[[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl ester

CAS: 198821-22-6

• Purity: 98%
• Molecular weight: 452.4670104980469

Merimepodib

CAS: 198821-22-6

Merimepodib is a research chemical that belongs to the group of inhibitors. It is commonly …

• Formula: C₂₃H₂₄N₄O₆
• Purity: Min. 95%
• Molecular weight: 452.47 g/mol