Description:Fmoc-D-Cit-OH, or 9-fluorenylmethoxycarbonyl-D-citrulline, is a protected amino acid commonly used in peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The presence of the D-citrulline moiety introduces unique properties, as citrulline is a non-standard amino acid that can influence the structure and function of peptides. Fmoc-D-Cit-OH is typically characterized by its stability under basic conditions, making it suitable for solid-phase peptide synthesis. Its solubility in organic solvents and moderate solubility in water facilitate its use in various chemical reactions. The compound is also notable for its role in the synthesis of peptides that require post-translational modifications or specific structural features, such as those found in biological systems. Overall, Fmoc-D-Cit-OH is a valuable building block in the field of peptide chemistry, contributing to the development of therapeutics and research tools.
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