CAS 2037-48-1: Deoxystreptamine

Description: Deoxystreptamine is a chemical compound that serves as a key structural component in various aminoglycoside antibiotics, such as streptomycin. It is characterized by its amino sugar structure, which contributes to its biological activity. The compound features multiple hydroxyl (-OH) groups and amino (-NH2) groups, which enhance its solubility in water and its ability to interact with bacterial ribosomes, thereby inhibiting protein synthesis. Deoxystreptamine is typically found in a cyclic form and exhibits a stereochemistry that is crucial for its antibiotic efficacy. Its mechanism of action primarily involves binding to the 30S ribosomal subunit, leading to misreading of mRNA and ultimately disrupting bacterial growth. Additionally, deoxystreptamine's properties make it a subject of interest in medicinal chemistry, particularly in the development of new antibiotics to combat resistant bacterial strains. Safety and handling precautions are essential when working with this compound, as with many antibiotics, due to potential toxicity and environmental impact.

Formula: C₆H₁₄N₂O₃

InChI: InChI=1/C6H14N2O3/c7-2-1-3(8)5(10)6(11)4(2)9/h2-6,9-11H,1,7-8H2/t2-,3+,4+,5-,6-

InChI key: InChIKey=DTFAJAKTSMLKAT-JDCCYXBGNA-N

SMILES: OC1C(O)C(N)CC(N)C1O

Synonyms:

• (1R,2r,3S,4R,6S)-4,6-diaminocyclohexane-1,2,3-triol
• (1R,3S,4R,6S)-4,6-diaminocyclohexane-1,2,3-triol
• 1,2,3-Cyclohexanetriol, 4,6-diamino-
• 2-Deoxy-<span class="text-smallcaps">D</span>-streptamine
• 2-Deoxystreptamine
• 2-Desoxystreptamine
• 2037-48-1
• 4,6-Diaminocyclohexane-1,2,3-Triol
• Deoxystreptamine
• Nsc 156938
• Streptamine, 2-deoxy-
• Streptamine, 2-deoxy- (8CI)(9CI)
• Streptamine, deoxy-

2-Deoxystreptamine dihydrobromide

CAS: 2037-48-1

• Molecular weight: 323.99

Gentamicin Sulfate EP Impurity E (2-Deoxystreptamine)

CAS: 2037-48-1

• Formula: C₆H₁₄N₂O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 162.19

2-Deoxystreptamine

CAS: 2037-48-1

2-Deoxystreptamine is an antimicrobial agent that inhibits the growth of bacteria by inhibiting protein synthesis. …

• Formula: C₆H₁₄N₂O₃
• Purity: Min. 95%
• Molecular weight: 162.19 g/mol