Description:Fmoc-D-homoleucine is a synthetic amino acid derivative commonly used in peptide synthesis and research. It features the Fmoc (9-fluorenylmethoxycarbonyl) protective group, which is widely utilized in solid-phase peptide synthesis to protect the amino group during the coupling reactions. The "D" in its name indicates that it is the D-enantiomer of homoleucine, which is an isomer of leucine with an additional carbon in its side chain, resulting in a branched structure. This modification can influence the peptide's conformation and biological activity. Fmoc-D-homoleucine is typically a white to off-white solid and is soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its molecular structure allows for the introduction of unique properties into peptides, making it valuable in the development of pharmaceuticals and bioconjugates. As with many synthetic compounds, handling should be done with care, following appropriate safety protocols.
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