CAS 209224-91-9: 5-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-3-amine

Description: 5-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-3-amine is a chemical compound characterized by its pyrazole core, which is a five-membered ring containing two nitrogen atoms. The presence of a trifluoromethyl group attached to a phenyl ring significantly influences its chemical properties, enhancing lipophilicity and potentially affecting its biological activity. This compound typically exhibits moderate to high stability under standard conditions, although it may be sensitive to strong acids or bases. Its structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to the presence of the amine functional group, which can participate in hydrogen bonding and enhance solubility in biological systems. Additionally, the trifluoromethyl group is known to improve metabolic stability and bioavailability. The compound's reactivity can be influenced by the electronic effects of the trifluoromethyl group, making it a subject of interest in synthetic organic chemistry and drug design. Safety and handling precautions should be observed, as with many organic compounds, to mitigate any potential hazards.

Formula: C₁₀H₈F₃N₃

InChI: InChI=1S/C10H8F3N3/c11-10(12,13)7-3-1-2-6(4-7)8-5-9(14)16-15-8/h1-5H,(H3,14,15,16)

InChI key: InChIKey=UKCQZEKREUKMTN-UHFFFAOYSA-N

SMILES: FC(F)(F)C1=CC=CC(=C1)C2=CC(=NN2)N

Synonyms:

• 1H-Pyrazol-3-amine, 5-[3-(trifluoromethyl)phenyl]-
• 1H-pyrazol-5-amine, 3-[3-(trifluoromethyl)phenyl]-
• 3-Amino-5-(3-trifluoromethylphenyl)-1H-pyrazole
• 3-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-5-amine
• 3-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-5-ylamine
• 5-(3-Trifluoromethylphenyl)-1H-pyrazol-3-amine
• 5-(3-Trifluoromethylphenyl)-2H-pyrazol-3-ylamine
• 5-Amino-3-[3-(trifluoromethyl)phenyl]-1H-pyrazole
• 5-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-3-ylamine
• Pyrazole-5-amine, 3-(3-trifluoromethylphenyl)-
• T5Mnj Cr Cxfff& Ez
• T5Mnj Cz Er Cxfff
• [5-(3-Trifluoromethylphenyl)-1H-pyrazol-3-yl]amine
• 5-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-3-amine

1H-Pyrazol-3-amine, 5-[3-(trifluoromethyl)phenyl]-

CAS: 209224-91-9

• Formula: C₁₀H₈F₃N₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 227.1858

5-(3-Trifluoromethylphenyl)-2H-pyrazol-3-ylamine

CAS: 209224-91-9

• Purity: 95.0%
• Molecular weight: 227.19000244140625

5-Amino-3-[3-(trifluoromethyl)phenyl]-1H-pyrazole

CAS: 209224-91-9

• Color and Shape: Crystals
• Molecular weight: 227.19g/mol

5-(3-Trifluoromethylphenyl)-2H-pyrazol-3-ylamine

CAS: 209224-91-9

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• Formula: C₁₀H₈F₃N₃
• Purity: Min. 95%
• Molecular weight: 227.19 g/mol