CAS 2119-75-7: Fluperolone acetate

Description: Fluperolone acetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is primarily used in dermatological formulations to treat various skin conditions, including eczema and dermatitis. The compound exhibits a high affinity for glucocorticoid receptors, which contributes to its effectiveness in reducing inflammation and modulating immune responses. Fluperolone acetate is characterized by its ability to penetrate the skin barrier, allowing for localized therapeutic effects with minimal systemic absorption. Its chemical structure includes a fluorinated steroid backbone, which enhances its potency and stability compared to non-fluorinated corticosteroids. The substance is typically formulated in topical preparations, such as creams or ointments, and is administered externally. Safety and efficacy profiles indicate that, while generally well-tolerated, prolonged use may lead to potential side effects, including skin atrophy or systemic effects if absorbed in significant amounts. As with any corticosteroid, it is essential to use Fluperolone acetate under medical supervision to mitigate risks and ensure appropriate therapeutic outcomes.

Formula: C₂₄H₃₁FO₆

InChI: InChI=1S/C24H31FO6/c1-13(31-14(2)26)20(29)23(30)10-8-17-18-6-5-15-11-16(27)7-9-21(15,3)24(18,25)19(28)12-22(17,23)4/h7,9,11,13,17-19,28,30H,5-6,8,10,12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1

InChI key: InChIKey=HHPZZKDXAFJLOH-QZIXMDIESA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CCC(O)(C(=O)C(OC(=O)C)C)C4(C)CC(O)C32F)C

Synonyms:

• (11β,17α)-17-[(2S)-2-(Acetyloxy)-1-oxopropyl]-9-fluoro-11,17-dihydroxyandrosta-1,4-dien-3-one
• (2S)-1-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-1-oxopropan-2-yl acetate (non-preferred name)
• 17(S)-[α-(Acetyloxy)-1-oxopropyl]-9-fluoro-11β,17α-dihydroxyandrosta-1,4-dien-3-one
• 17β-[2-Acetoxypropionyl]-9α-fluoro-11β,17-dihydroxyandrosta-1,4-dien-3-one
• 21-Methyl-9α-fluoroprednisolone acetate
• 9-Fluoro-11beta,17alpha-dihydroxy-17-(S)-lactoylandrosta-1,4-dien-3-one 17beta-acetate
• 9-Fluoro-11beta,17alpha-hydroxy-17-lactoylandrosta-1,4-diene 17beta-acetate
• 9α-Fluoro-11β,17α,21-trihydroxy-21-methylpregna-1,4-diene-3,20-dione 21-acetate
• Alacortril
• Androsta-1,4-dien-3-one, 17-(2-(acetyloxy)-1-oxopropyl)-9-fluoro-11,17-dihydroxy-, (11beta,17alpha,17(S))-
• Androsta-1,4-dien-3-one, 17-[(2S)-2-(acetyloxy)-1-oxopropyl]-9-fluoro-11,17-dihydroxy-, (11β,17α)-
• Androsta-1,4-dien-3-one, 17-[2-(acetyloxy)-1-oxopropyl]-9-fluoro-11,17-dihydroxy-, [11β,17α,17(S)]-
• Androsta-1,4-dien-3-one, 9-fluoro-11β,17α-dihydroxy-17-(S)-lactoyl-, 17β-acetate
• Falban-Crema
• Flu-Korti
• Fluperolone 21-acetate
• Fluperolone acetate
• Fluperolone acetate [USAN]
• Methral
• P 1742

Fluperolone Acetate

CAS: 2119-75-7

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Neat
• Molecular weight: 434.498

Fluperolone acetate

CAS: 2119-75-7

Fluperolone acetate is a synthetic steroid that has been used as an anti-inflammatory agent. It …

• Formula: C₂₄H₃₁FO₆
• Purity: Min. 95%
• Molecular weight: 434.5 g/mol

Fluperolone acetate

CAS: 2119-75-7

Fluperolone acetate is a Glucocorticoid/Adrenal Cortex Hormone.

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Solid
• Molecular weight: 434.50