CAS 213594-60-6: Balsalazide disodium

Description: Balsalazide disodium is a chemical compound primarily used as a medication for the treatment of ulcerative colitis, a form of inflammatory bowel disease. It is classified as a 5-aminosalicylic acid (5-ASA) derivative, which exerts its therapeutic effects by reducing inflammation in the colon. The compound is a disodium salt of balsalazide, which is formed by the combination of 5-ASA and an inert carrier molecule. Balsalazide disodium is characterized by its ability to release 5-ASA in the colon, where it acts topically to alleviate symptoms. The compound is typically administered orally and is known for its relatively low side effect profile compared to other treatments for ulcerative colitis. In terms of its chemical structure, it features a complex arrangement that includes aromatic rings and carboxylic acid functional groups, contributing to its solubility and bioactivity. Overall, balsalazide disodium represents an important therapeutic option for managing inflammatory bowel conditions.

Formula: C₁₇H₁₃N₃Na₂O₆

InChI: InChI=1/C17H15N3O6.2Na/c21-14-5-4-12(9-13(14)17(25)26)20-19-11-3-1-2-10(8-11)16(24)18-7-6-15(22)23;;/h1-5,8-9,21H,6-7H2,(H,18,24)(H,22,23)(H,25,26);;/q;2*+1/p-2

Synonyms:

• Disodium (3E)-3-[[4-[(3-oxido-3-oxopropyl)carbamoyl]phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylate
• disodium (3E)-3-({4-[(2-carboxylatoethyl)carbamoyl]phenyl}hydrazono)-6-oxocyclohexa-1,4-diene-1-carboxylate
• disodium (3Z)-3-({4-[(2-carboxylatoethyl)carbamoyl]phenyl}hydrazono)-6-oxocyclohexa-1,4-diene-1-carboxylate
• disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate
• [2-Hydroxy-5-[3-[(3-Oxo-3-Sodiooxy-Propyl)Carbamoyl]Phenyl]Azo-Benzoyl]Oxysodium

Balsalazide disodium

CAS: 213594-60-6

Balsalazide disodium is a prodrug that converts to balsalazide in the gastrointestinal tract. It has …

• Formula: C₁₇H₁₅N₃O₆·2Na
• Purity: Min. 95%
• Molecular weight: 403.3 g/mol