CAS 214748-66-0: (5Z,9β,11β,12α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid

Description: The chemical substance known as (5Z,9β,11β,12α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid, with the CAS number 214748-66-0, is a member of the prostaglandin family, which are bioactive lipids derived from arachidonic acid. This compound features multiple hydroxyl groups, indicating its potential for strong hydrogen bonding and solubility in polar solvents. Its structure includes a series of double bonds and a carboxylic acid functional group, which contribute to its reactivity and biological activity. Prostaglandins are known for their roles in various physiological processes, including inflammation, pain modulation, and regulation of blood flow. The specific stereochemistry of this compound, denoted by the various stereocenters, is crucial for its biological function, as it influences how the molecule interacts with specific receptors in the body. Overall, this compound exemplifies the complexity and significance of prostaglandins in biochemistry and pharmacology.

Formula: C₂₀H₃₄O₅

InChI: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17-,18+,19-/m0/s1

InChI key: InChIKey=PXGPLTODNUVGFL-XNTKLVSTSA-N

SMILES: O=C(O)CCCC=CCC1C(O)CC(O)C1C=CC(O)CCCCC

Synonyms:

• (5Z,9β,11β,12α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid
• Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9β,11β,12α,13E,15S)-

ent-8-iso-15(S)-Prostaglandin F2α

CAS: 214748-66-0

Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid.

• Formula: C₂₀H₃₄O₅
• Color and Shape: Liquid
• Molecular weight: 354.48