CAS 215777-46-1: 7-36-Glucagon-likepeptide I (human), 8-L-serine-36-L-argininamide-

Description:7-36-Glucagon-like peptide I (human), 8-L-serine-36-L-argininamide, commonly referred to as GLP-1, is a peptide hormone that plays a crucial role in glucose metabolism and appetite regulation. It is derived from the proglucagon gene and is primarily secreted by the intestinal L-cells in response to food intake. This peptide consists of 36 amino acids and is characterized by its ability to stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, thereby helping to lower blood glucose levels. Additionally, GLP-1 inhibits glucagon release, slows gastric emptying, and promotes satiety, making it a target for diabetes treatment and obesity management. The CAS number 215777-46-1 identifies this specific peptide, which is often used in research and therapeutic applications. Its stability and activity can be influenced by modifications to its structure, such as the addition of amino acids like L-serine and L-arginine, which can enhance its pharmacological properties. Overall, GLP-1 is a vital component in the regulation of metabolic processes and has significant implications in the treatment of type 2 diabetes.

Formula:C₁₄₉H₂₂₆N₄₀O₄₆

Synonyms:
7-36-Glucagon-likepeptide 1 (Octodon degus), 8-L-serine-36-L-argininamide- (9CI)
L-Argininamide, L-histidyl-L-seryl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-
(Ser79)-Proglucagon (78-107) Amide (Human, Bovine, Guinea Pig, Mouse, Rat) Trifluoroacetate Salt
22: PN:WO0155213 SEQID: 22 claimed sequence

Found 2 products.

Brand	Product data	Purity	Price range	Estimated delivery
	(Ser⁸)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) REF: 01-4029130CAS: 215777-46-1	95.2%	314.00 €~555.00 €	Tue 25 Mar 25
	(Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt REF: 3D-FS109310CAS: 215777-46-1	Min. 95%	366.00 €~3,267.00 €	Thu 22 May 25