CAS 26605-16-3: Desferrioxamine E

Description: Desferrioxamine E is a chelating agent primarily used in the treatment of iron overload conditions, such as those resulting from repeated blood transfusions in patients with conditions like thalassemia. It is a member of the desferrioxamine family, which are hydroxamic acid derivatives that effectively bind free iron ions, facilitating their excretion from the body. This compound is characterized by its ability to form stable complexes with ferric ions, thus preventing iron from participating in harmful biochemical reactions that can lead to oxidative stress and tissue damage. Desferrioxamine E is typically administered parenterally, as its oral bioavailability is limited. In addition to its therapeutic applications, it has been studied for its potential use in various research contexts, including its role in cellular iron metabolism and its effects on microbial growth. The compound is generally recognized for its safety profile, although potential side effects may include allergic reactions and gastrointestinal disturbances. Overall, Desferrioxamine E plays a crucial role in managing iron overload and is an important tool in clinical settings.

Formula: C₂₇H₄₈N₆O₉

InChI: InChI=1S/C27H48N6O9/c34-22-10-14-26(38)32(41)20-8-3-6-18-30-24(36)12-15-27(39)33(42)21-9-2-5-17-29-23(35)11-13-25(37)31(40)19-7-1-4-16-28-22/h40-42H,1-21H2,(H,28,34)(H,29,35)(H,30,36)

InChI key: InChIKey=NHKCCADZVLTPPO-UHFFFAOYSA-N

SMILES: O=C1NCCCCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(=O)CC1

Synonyms:

• 1,6,12,17,23,28-Hexaazacyclotritriacontane-2,5,13,16,24,27-hexone, 1,12,23-trihydroxy-
• 26605-16-3
• Deferriferrioxamine E
• Deferrioxamine E
• Desferrioxamine E
• Nocardamin
• Nocardamine
• Proferrioxamine E
• 1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone

1,6,12,17,23,28-Hexaazacyclotritriacontane-2,5,13,16,24,27-hexone, 1,12,23-trihydroxy-

CAS: 26605-16-3

• Formula: C₂₇H₄₈N₆O₉
• Molecular weight: 600.7048

Nocardamine

CAS: 26605-16-3

Nocardamine, a Streptomyces siderophore, chelates iron (IC50=9.9 μM), inhibits biofilms (MIC=10 μM), is cytotoxic to …

• Formula: C₂₇H₄₈N₆O₉
• Color and Shape: Liquid
• Molecular weight: 600.7

Nocardamine

CAS: 26605-16-3

• Formula: C₂₇H₄₈N₆O₉
• Purity: ≥ 95.0%
• Color and Shape: White to off-white solid
• Molecular weight: 600.70

Nocardamine

CAS: 26605-16-3

• Formula: C₂₇H₄₈N₆O₉
• Color and Shape: Neat
• Molecular weight: 600.705

Nocardamine

CAS: 26605-16-3

Nocardamine is a chemical compound with antimicrobial activity. It is a cyclic peptide that has …

• Formula: C₂₇H₄₈N₆O₉
• Purity: Min. 95%
• Molecular weight: 600.71 g/mol