CAS 27460-26-0: (24R)-Hydroxycholesterol

Description: (24R)-Hydroxycholesterol is a sterol and a derivative of cholesterol, characterized by the presence of a hydroxyl group at the 24th carbon position in its steroid structure. This compound plays a significant role in cholesterol metabolism and is involved in various biological processes, including the regulation of cholesterol homeostasis and the modulation of gene expression. It is primarily synthesized in the brain and is known to influence neuronal function and development. As a signaling molecule, (24R)-hydroxycholesterol can cross the blood-brain barrier and is implicated in neuroprotective mechanisms. Its structure contributes to its amphipathic nature, allowing it to interact with cell membranes and proteins. The compound is also studied for its potential implications in neurodegenerative diseases and other health conditions related to cholesterol dysregulation. Due to its biological significance, (24R)-hydroxycholesterol is of interest in both pharmacological research and clinical studies.

Formula: C₂₇H₄₆O₂

InChI: InChI=1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25-,26+,27-/m1/s1

InChI key: InChIKey=IOWMKBFJCNLRTC-RNCHBCSGSA-N

SMILES: OC1CC2=CCC3C(CCC4(C)C(CCC34)C(C)CCC(O)C(C)C)C2(C)CC1

Synonyms:

• 24-Epicerebrosterol
• Cholest-5-ene-3,24-diol, (3β,24R)-
• Cholest-5-ene-3β,24-diol, (24R)-
• (3β,24R)-Cholest-5-ene-3,24-diol
• (24R)-Hydroxycholesterol

24(R)-Hydroxycholesterol

CAS: 27460-26-0

• Formula: C27H46O2
• Purity: >98%
• Color and Shape: Solid
• Molecular weight: 402.65

24-Epicerebrosterol

CAS: 27460-26-0

• Formula: C₂₇H₄₆O₂
• Color and Shape: Neat
• Molecular weight: 402.65

24(R)-hydroxycholesterol

CAS: 27460-26-0

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• Formula: C₂₇H₄₆O₂
• Purity: Min. 95%
• Molecular weight: 402.65 g/mol