CAS: 801-52-5 - Porfiromycin

Formula: C₁₆H₂₀N₄O₅

InChI: InChI=1S/C16H20N4O5/c1-6-10(17)13(22)9-7(5-25-15(18)23)16(24-3)14-8(19(14)2)4-20(16)11(9)12(6)21/h7-8,14H,4-5,17H2,1-3H3,(H2,18,23)/t7-,8+,14+,16-,19?/m1/s1

InChI key: InChIKey=HRHKSTOGXBBQCB-VFWICMBZSA-N

SMILES: O=C(OCC1C=2C(=O)C(N)=C(C(=O)C2N3CC4N(C)C4C31OC)C)N

Synonyms:

• (1aS,8S,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethylazirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione
• (6-Amino-8A-Methoxy-1,5-Dimethyl-4,7-Dioxo-1,1A,2,4,7,8,8A,8B-Octahydroazireno[2',3':3,4]Pyrrolo[1,2-A]Indol-8-Yl)Methyl Carbamate
• 6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-1,5-dimethylazirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione carbamate (ester)
• Ai3-50825
• Azirino(2',3':3,4)pyrrolo(1,2-a)-indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-
• Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a- methoxy-1,5-dimethyl-, carbamate (ester) (8CI)
• Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-1,5-dimethyl-, carbamate (ester)
• Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-1,5-dimethyl-,(1aR-(1aalpha,8beta,8aalpha,8balpha))- (9CI)
• Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-1,5-dimethyl-, carbamate (ester)
• Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-, (1aS,8S,8aR,8bS)-
• Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-, [1aS-(1aα,8β,8aα,8bα)]-
• Ent-50825
• Methyl mitomycin C
• Methylmitomycin
• Mitomycin C, N-methyl-
• N-Methylmitomycin C
• Nci 56410
• Nsc 56410
• Porfiromicina
• Porfiromicina [INN-Spanish]
• Porfiromycin [USAN:INN:BAN]
• Porfiromycine
• Porfiromycine [INN-French]
• Porfiromycinum
• Porfiromycinum [INN-Latin]
• Porphyromycin
• Regamycin
• U-14743
• Unii-H1Wk901Oa6
• [(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate

Porfiromycin

CAS: 801-52-5

Applications Antibiotic substance isolated from a Streptomyces ardus fermentation broth. Antibacterial; antineoplastic. Not a dangerous …

• Formula: C₁₆H₂₀N₄O₅
• Color and Shape: Purple To Black
• Molecular weight: 348.35

Porfiromycin

CAS: 801-52-5

Porfiromycin is a cytotoxic compound that inhibits the cell cycle progression by binding to DNA …

• Formula: C₁₆H₂₀N₄O₅
• Purity: Min. 95 Area-%
• Color and Shape: Powder
• Molecular weight: 348.35 g/mol

Porfiromycin

CAS: 801-52-5

Porfiromycin, a mitomycin C derivative from Streptomyces, alkylates DNA and targets hypoxic cells.

• Formula: C₁₆H₂₀N₄O₅
• Color and Shape: Liquid
• Molecular weight: 348.35