CAS: 882976-95-6 - (3S,3aR,7R,8R,9S,10aR,12aS,12bR)-9-(Dimethylamino)-1,2,3,3a,4,7,8,9,10,11,12,12b-dodecahydro-3-(7-isoquinolinyl)-3a-methyl-10a,12a-epoxybenzo[4,5]cyclohept[1,2-e]indene-7,8-diol

Formula: C₃₀H₃₆N₂O₃

InChI: InChI=1S/C30H36N2O3/c1-28-10-8-21-15-23-26(33)27(34)24(32(2)3)16-29(23)11-12-30(21,35-29)25(28)7-6-22(28)19-5-4-18-9-13-31-17-20(18)14-19/h4-5,8-9,13-15,17,22,24-27,33-34H,6-7,10-12,16H2,1-3H3/t22-,24+,25-,26-,27-,28-,29-,30-/m1/s1

InChI key: InChIKey=KSGZCKSNTAJOJS-DZBMUNJRSA-N

SMILES: OC1C2=CC3=CCC4(C)C(C=5C=CC=6C=CN=CC6C5)CCC4C73OC2(CC7)CC(N(C)C)C1O

Synonyms:

• (+)-Cortistatin A
• (3S,3aR,7R,8R,9S,10aR,12aS,12bR)-9-(Dimethylamino)-1,2,3,3a,4,7,8,9,10,11,12,12b-dodecahydro-3-(7-isoquinolinyl)-3a-methyl-10a,12a-epoxybenzo[4,5]cyclohept[1,2-e]indene-7,8-diol
• Cortistatin A
• Cortistatine A
• 10a,12a-Epoxybenzo[4,5]cyclohept[1,2-e]indene-7,8-diol, 9-(dimethylamino)-1,2,3,3a,4,7,8,9,10,11,12,12b-dodecahydro-3-(7-isoquinolinyl)-3a-methyl-, (3S,3aR,7R,8R,9S,10aR,12aS,12bR)-

Cortistatin A

CAS: 882976-95-6

Cortistatin A is a potent and selective mediator-associated kinase CDK8 and its paralogue CDK19 inhibitor.

• Formula: C₃₀H₃₆N₂O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 472.62