CAS 913376-84-8: N-[3-Fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl]-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide

Formula: C₃₁H₂₉FN₄O₅

InChI: InChI=1S/C31H29FN4O5/c1-19-28(30(38)36(21-8-6-5-7-9-21)35(19)18-31(2,3)39)29(37)34-20-10-13-27(24(32)16-20)41-26-14-15-33-25-17-22(40-4)11-12-23(25)26/h5-17,39H,18H2,1-4H3,(H,34,37)

InChI key: InChIKey=UYMSIPINLJNNOU-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(OC=2C=CN=C3C=C(OC)C=CC32)C(F)=C1)C=4C(=O)N(C=5C=CC=CC5)N(C4C)CC(O)(C)C

Synonyms:

• 1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[(7-methoxy-4-quinolinyl)oxy]phenyl]-2,3-dihydro-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-
• SYN 1143
• Kin237
• N-[3-Fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl]-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
• N-[3-Fluoro-4-[(7-methoxy-4-quinolinyl)oxy]phenyl]-2,3-dihydro-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-1H-pyrazole-4-carboxamide

AMG-1

CAS: 913376-84-8

• Formula: C₃₁H₂₉FN₄O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 556.5842

SYN1143

CAS: 913376-84-8

SYN1143 (AMG-1) strongly inhibits RON & c-Met with IC50s: 9 & 4 nmol/L.

• Formula: C₃₁H₂₉FN₄O₅
• Purity: 98.86%
• Color and Shape: Solid
• Molecular weight: 556.58

AMG-1

CAS: 913376-84-8

N-[3-Fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl]-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-ca rboxamide

CAS: 913376-84-8

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• Formula: C₃₁H₂₉FN₄O₅
• Purity: Min. 95%
• Molecular weight: 556.58 g/mol