ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
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Desoxo-narchinol A
CAS:53859-06-6
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it …
Formula:
C12H16O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
192.25
Ref: TM-TN3839
| 1mg | 397.00 € | ||
| 5mg | 1,954.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Lupalbigenin
CAS:76754-24-0
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
Formula:
C25H26O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
406.47
Ref: TM-TN1889
| 1mg | 800.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
EphB2 Protein, Human, Recombinant (His & hFc)
EphB2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His …
Color and Shape:
Liquid
Molecular weight:
86 kDa (predicted)
Ref: TM-TMPY-00784
| 100µg | 589.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Enniatin B1
CAS:19914-20-6
Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier and modulates ERK, NF-κB, and ACAT …
Formula:
C34H59N3O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
653.858
Ref: TM-T13680
| 1mg | 665.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
EphB2 Protein, Mouse, Recombinant (hFc)
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
Color and Shape:
Liquid
Molecular weight:
84.6 kDa (predicted); 96.6 kDa (reducing conditions)
Ref: TM-TMPY-03621
| 200µg | 499.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Hydroxycitric acid
CAS:6205-14-7
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of …
Formula:
C6H8O8
Color and Shape:
Solid
Molecular weight:
208.12
Ref: TM-TN1751
| 20mg | 65.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Bongkrekic acid
CAS:11076-19-0
Bongkrekic acid (Bongkrekic Acid (ammonium salt)) is a mitochondrial toxin secreted by Burkholderia cepacia that …
Formula:
C28H38O7
Color and Shape:
Liquid
Molecular weight:
486.6
Ref: TM-T36067
| 1mg | 1,632.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Enniatin B
CAS:917-13-5
Enniatins B decreases the activation of ERK (p44/p42).
Formula:
C33H57N3O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
639.831
Ref: TM-T13679
| 1mg | 605.00 € | ||
| 5mg | 2,681.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
A-674563
CAS:552325-73-2
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and …
Formula:
C22H22N4O
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
358.44
Ref: TM-T6139
| 1mg | 51.00 € | ||
| 5mg | 109.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Broussonin E
CAS:90902-21-9
Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and …
Formula:
C17H20O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
288.34
Ref: TM-TN3541
| 1mg | 696.00 € | ||
| 5mg | 1,392.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
EphB2 Protein, Human, Recombinant (His)
EphB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Color and Shape:
Liquid
Molecular weight:
59.7 kDa (predicted)
Ref: TM-TMPY-01067
| 100µg | 588.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
ERK2 Protein, Human, Recombinant (GST)
ERK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.
Color and Shape:
Liquid
Molecular weight:
67 kDa (predicted); 67 kDa (reducing conditions)
Ref: TM-TMPY-04539
| 50µg | 399.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PERK-IN-2
CAS:1337531-83-5
PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).
Formula:
C23H18F3N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
437.42
Ref: TM-T12409
| 2mg | 88.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
EM127
CAS:1886879-71-5
EM127: covalent SMYD3 inhibitor, KD 13μM, impedes ERK1/2, hinders SMYD3 gene regulation, long-term methyltransferase reduction, …
Formula:
C14H18ClN3O3
Purity:
97.61%
Color and Shape:
Liquid
Molecular weight:
311.76
Ref: TM-T60777
| 5mg | 102.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 347.00 € | ||
| 50mg | 557.00 € | ||
| 100mg | 887.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Licochalcone D
CAS:144506-15-0
Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and …
Formula:
C21H22O5
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
354.4
Ref: TM-T4518
| 1mg | 94.00 € | ||
| 5mg | 222.00 € | ||
| 10mg | 322.00 € | ||
| 25mg | 535.00 € | ||
| 50mg | 763.00 € | ||
| 100mg | 1,011.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nitidine chloride
CAS:13063-04-2
1.
Formula:
C21H18ClNO4
Purity:
96.59% - 98.91%
Color and Shape:
Solid
Molecular weight:
383.82
Ref: TM-T5S0761
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 441.00 € | ||
| 500mg | 916.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
XMD17-109
CAS:1435488-37-1
XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).
Formula:
C36H46N8O3
Purity:
98.86% - 99.75%
Color and Shape:
Solid
Molecular weight:
638.8
Ref: TM-T1842
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 527.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LM22B-10
CAS:342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and …
Formula:
C27H33ClN2O4
Purity:
98.19%
Color and Shape:
Solid
Molecular weight:
485.01
Ref: TM-T4496
| 1mg | 39.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 272.00 € | ||
| 50mg | 429.00 € | ||
| 100mg | 682.00 € | ||
| 1mL*10mM (DMSO) | 132.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(E/Z)-BIX02188
CAS:1094614-84-2
BIX02188 inhibits MEK5 (IC50: 4.3 nM) and ERK5 (810 nM) but not MEK1/2, JNK2, or …
Formula:
C25H24N4O2
Purity:
97.39% - 98.38%
Color and Shape:
Solid
Molecular weight:
412.48
Ref: TM-T6324
| 1mg | 51.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 341.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 737.00 € | ||
| 1mL*10mM (DMSO) | 142.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
A-674563 2HCl(552325-73-2(fb-2hcl))
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA …
Formula:
C22H24Cl2N4O
Purity:
94.66%
Color and Shape:
Solid
Molecular weight:
431.36
Ref: TM-T6139L
| 1mg | 85.00 € | ||
| 5mg | 137.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 332.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 722.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
