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Tyrosine Kinases

Tyrosine Kinases

Tyrosine kinase inhibitors are a broad class of compounds that inhibit tyrosine kinases, enzymes responsible for the transfer of a phosphate group to tyrosine residues on proteins, which is a critical step in cell signaling. Dysregulation of tyrosine kinases is implicated in many cancers and other diseases. These inhibitors are essential tools in the study of cell signaling pathways, cancer research, and the development of targeted therapies. At CymitQuimica, we provide a wide range of tyrosine kinase inhibitors to support your research in oncology, cell biology, and therapeutic development.

Found 27 products of "Tyrosine Kinases"

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  • NVP-BSK805
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    NVP-BSK805

    CAS:
    <p>NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.</p>
    Formula:C27H28F2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490.55

    Ref: TM-T5049

  • JAK-IN-21
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    JAK-IN-21

    CAS:
    <p>JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 with IC50 values of 1.73, 2.04, 109 and 62.9 nM, respectively.</p>
    Formula:C19H16N8O
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:372.38

    Ref: TM-T61494

  • GSK-2250665A
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    GSK-2250665A

    CAS:
    <p>GSK-2250665A is an (Itk) inhibitor (pKi 9.2) with selectivity over Aurora B and Btk, inhibiting IFNγ in PBMCs for T-cell signaling studies.</p>
    Formula:C26H29N5OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:459.61

    Ref: TM-T27458

  • Brepocitinib
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    Brepocitinib

    CAS:
    <p>Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).</p>
    Formula:C18H21F2N7O
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:389.4

    Ref: TM-TQ0010

  • Ropsacitinib
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    Ropsacitinib

    CAS:
    <p>Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).</p>
    Formula:C20H17N9
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:383.41

    Ref: TM-T13237L

  • ITK inhibitor 2
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    ITK inhibitor 2

    CAS:
    <p>ITK inhibitor 2 (compound 4) is a potent and selective ITK inhibitor with an IC50= 2 nM.</p>
    Formula:C25H33N5O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:435.56

    Ref: TM-T11690

  • Vecabrutinib
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    Vecabrutinib

    CAS:
    <p>Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.</p>
    Formula:C22H24ClF4N7O2
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:529.92

    Ref: TM-T17220