CAS 21259-20-1

Toxin T 2

Beschreibung:

Toxin T 2, mit der CAS-Nummer 21259-20-1, ist ein Mykotoxin, das von bestimmten Pilzarten, insbesondere solchen der Gattung Fusarium, produziert wird. Es wird als Trichothecen klassifiziert, eine Gruppe von Toxinen, die für ihre Fähigkeit bekannt sind, die Proteinsynthese in eukaryotischen Zellen zu hemmen, was zu einer Reihe von toxischen Effekten führt. Toxin T 2 zeichnet sich durch seine starke Zytotoxizität und immunsuppressiven Eigenschaften aus, die sowohl die menschliche als auch die tierische Gesundheit beeinträchtigen können. Die Exposition gegenüber diesem Toxin kann durch kontaminierte Lebensmittel oder Futtermittel erfolgen und ist mit verschiedenen Gesundheitsproblemen verbunden, darunter gastrointestinale Störungen, Hautreizungen und schwerwiegendere systemische Effekte bei höheren Dosen. Die Verbindung ist auch für ihre Stabilität unter verschiedenen Umweltbedingungen bekannt, was sie in landwirtschaftlichen Kontexten zu einem Anliegen macht. Aufgrund ihrer Toxizität unterliegt Toxin T 2 einer regulatorischen Überprüfung, und es werden Anstrengungen unternommen, um ihre Präsenz in Lebensmitteln zu überwachen und zu begrenzen, um die Sicherheit zu gewährleisten.

Formel: C₂₄H₃₄O₉

InChl: InChI=1/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1

InChI Key: InChIKey=BXFOFFBJRFZBQZ-QYWOHJEZSA-N

SMILES: C[C@@]12[C@@]3([C@@]([C@H](O)[C@H]1OC(C)=O)(O[C@]4([C@]2(COC(C)=O)C[C@H](OC(CC(C)C)=O)C(C)=C4)[H])[H])CO3

Synonyme:

• (3Α,4Β,8Α)-12,13-Epoxytrichothec-9-Ene-3,4,8,15-Tetrol 4,15-Diacetate 8-(3-Methylbutyrate)
• (3α,4β,8α)-12,13-Epoxytrichothec-9-en-3,4,8,15-tetrol-4,15-diacetat-8-(3-methylbutyrat)
• 4,15-Diacetate-8-(3-Methylbutyrate) De (3Α,4Β,8Α)-12,13-Epoxytrichothec-9-Ene-3,4,8,15-Tetrol
• 4,15-Diacetato-8-(3-Metilbutirato) De (3Α,4Β,8Α)-12,13-Epoxitricotec-9-Eno-3,4,8,15-Tetrol
• 4β,15-Diacetoxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en-3α-ol
• 8α-(3-Methylbutyryloxy)-4β,15-diacetoxyscirp-9-en-3α-ol
• Fusariotoxin T 2
• Insariotoxin
• Mycotoxin T 2
• Nsc 138780
• Spiro[2,5-methano-1-benzoxepin-10,2′-oxirane], trichothec-9-ene-3,4,8,15-tetrol deriv.
• T 2
• T 2 Toxin
• T 2 mycotoxin
• T-2 Lienomycin
• Toxin T 2
• Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-isovalerate
• (3beta,4alpha,8alpha)-4,15-bis(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), (3α,4β,8α)-
• T-2 toxin from fusarium sp
• Epoxytrichothecene, Fusariotoxin T 2, Mycotoxin T 2
• 3alpha-hydroxy-4beta-15-diacetoxy-8alpha-(3-methylbutyryloxy)-12,13-epoxy-delt
• 3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta(sup9)-tric
• 12,13-epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate
• trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-,4,15-diacetate8-(3-methylbutan
• 3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-(sup9)-trich
• 3-hydroxy-4,15-diacetoxy-8-[3-methylbutyryloxy]-12,13-epoxytrichothec-9-ene
• a9-tricothecene[qr]
• 4BETA,15-DIACETOXY-3ALPHA-HYDROXY-8ALPHA-[3-METHYLBUTYRYLOXY]-12,13-EPOXYTRICHOTHEC-9-ENE
• -isovalerate
• nsc138780[qr]
• 100 ug/ml T-2 Toxin in ACN
• 4-beta,15-diacetoxy-8-alpha-(3-methylbutyryloxy)-3-alpha-hydroxy-12,13-epoxy
• 13C24]-T-2 toxin-25 μg/mL in ACN
• 8-(3-methylbutyryloxy)-diacetoxyscirpenol[qr]
• T-2 Toxin, 99%, from Fusarium tricinctum
• t2-trichothecene[qr]
• 8alpha-(3-Methylbutyryloxy)-4beta,15-diacetoxyscirp-9-en-3alpha-ol
• CAS21259-20-1 T-2 TOXIN
• T2 Toxin / Fusariotoxin T 2 / Insariotoxin / Mycotoxin T 2
• T2 toxin 100ug/ml in ACN
• hothecene
• 12,13-trichothecene
• Fusariotoxin T2: (T2-Trichothecene)
• FUSARITOXIN
• 8α-(3-Methylbutyryloxy)-4β,15-
• Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-isovalerate
• t-2mycotoxin[qr]
• 12,13-EPOXYTRICHOTHECENE
• T-2 Toxin Solution in Acetonitrile, 100μg/mL
• 8alpha-(3-methylbutyryloxy)-4beta,15-diacetoxyscirp-9-en-3alpha-ol[qr]
• 8-(3-Methylbutyryloxy)diacetoxyscirpenol
• 3alpha-Hydroxy-4beta,15-diacetoxy-8alpha(3-methylbutyryloxy)-12,13-epoxy-trichothec-9-ene
• 4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-9-trichothecen-3-ol
• (3-ALPHA, 4-BETA, 8-ALPHA)-TRICHOTHEC-9-ENE-3,4,8,15-TETROL,12,13-EPOXY-, 4,15-DIACETATE 8-(3-METHYLBUTANOATE)
• 8-(3-methylbutyryloxy)-diacetoxyscirpenol
• 12,13-epoxytrichothec-9-ene-3alpha,4beta,8alpha,15-tetrol,4,15-diacetate8-isov
• (3-alpha, 4-beta, 8-alpha)-Trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), Mycotoxin Trichothecene 2, Fusariotoxin
• 4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-9-trichothecen-3-ol[qr
• U-[13C24]-T-2 Toxin Solution in Acetonitrile, 25μg/mL
• MYCOTOXIN TRICHOTHECENE 2
• alerate[qr]
• 4β,15-Diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene, 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate
• EPOXYTRICHOTHECENE
• isaritoxin[qr]
• 12,13-epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol4,15-diacetate8
• T-2TRICHOTHECENE
• 4β,15-Diacetoxy-8α-(3-Methylbutyryloxy)-
• T-2-toxin vial with 5 mg
• 12,13-epoxytrichothec-9-ene-3,4,8,15-tetrol4,15-diacetate8-(3-methylbutanoate
• T-2 Toxin (T-2 Mycotoxin)
• toxint2
• trichothec-9-ene
• 4beta,8alpha,15-tetrol,12,13-epoxy-,4,15-diacetate8-trichothec-9-ene-3alph
• (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-Diacetate 8-(3-Methylbutanoate)
• T-2 Toxin,12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 4β,15-Diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
• (3alpha,4beta,8alpha)-12,13-epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-diacetate 8-(3-methylbutyrate)
• (3alpha,4beta,8alpha)-oate
• 4,15-diacetoxy-8-(3-methylbutyryloxy)scirp-9-en-3-ol
• 8-isovalerate
• t-2mycotoxin
• fusariotoxinet2
• 8-(3-methylbutyryloxy)-diacetoxy-scirpeno
• fusariotoxinet2[qr]
• T-2 Toxin, froM FusariuM tricinctuM
• 12,13-epoxytrichothec-9-en-3α-ol
• trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol,12,13-epoxy-,4,15-diacetate
• Scirpenol, 8-(3-methylbutyryloxy)-diacetoxy-
• t(sub2)-trichothecene[qr]
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-
• FUSARIOTOXIN
• diacetoxyscirp-9-en-3α-ol
• nsc138780
• othecene[qr]

T-2 Toxin 100 µg/mL in Acetonitrile

Kontrolliertes Produkt

CAS: 21259-20-1

Formel: C₂₄H₃₄O₉

Farbe und Form: Single Solution

Molekulargewicht: 466.52

Ref: 04-A13989000AL-100

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Kontrolliertes Produkt

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8

Farbe und Form: Mixture

Ref: 04-A30000004AL

T-2 Toxin

Kontrolliertes Produkt

CAS: 21259-20-1

Formel: C₂₄H₃₄O₉

Farbe und Form: Neat

Molekulargewicht: 466.52

Ref: 04-C13989000-5MG

T-2 Toxin

Kontrolliertes Produkt

CAS: 21259-20-1

Formel: C₂₄H₃₄O₉

Farbe und Form: Neat

Molekulargewicht: 466.52

Ref: 04-C13989000-10MG

Fusarium Toxins Mixture 10-100 µg/mL in Acetonitrile

Kontrolliertes Produkt

CAS: 17924-92-4, 21259-20-1, 26934-87-2, 51481-10-8, 5975-78-0

Farbe und Form: Mixture

Ref: 04-V30000007AL

T-2 Toxin 100 µg/mL in Acetonitrile

Kontrolliertes Produkt

CAS: 21259-20-1

Formel: C₂₄H₃₄O₉

Farbe und Form: Single Solution

Molekulargewicht: 466.52

Ref: 04-V13989000AL-100

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Kontrolliertes Produkt

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8, 5975-78-0

Farbe und Form: Mixture

Ref: 04-V30000004AL

T-2 Toxin

CAS: 21259-20-1

Formel: C₂₄H₃₄O₉

Molekulargewicht: 466.53

Ref: 4Z-M-214001

T-2 Toxin

CAS: 21259-20-1

Formel: C₂₄H₃₄O₉

Reinheit: ≥ 98.0%

Farbe und Form: White to off-white solid

Molekulargewicht: 466.52

Ref: 7W-GW6303

T2 Toxin

Kontrolliertes Produkt

CAS: 21259-20-1

T2 toxin is a toxin produced by the bacterium Bacillus thuringiensis. It has an inhibitory effect on the polymerase chain reaction (PCR) and is toxic to cells in vitro. T2 toxin inhibits mitochondrial function, which can lead to cell death. T2 toxin also has antioxidant properties, and may have therapeutic potential as a drug transporter. The optimum concentration of T2 toxin for toxicity studies is unknown, but it has been shown that concentrations greater than 10 µg/mL are toxic to cells in vitro. In addition, T2 toxin has been shown to be toxic to human serum and liver cells at high concentrations.

Reinheit: Min. 95%

Farbe und Form: Powder

Ref: 3D-BT162749

T-2 Toxin

CAS: 21259-20-1

T-2 Toxin

Formel: C₂₄H₃₄O₉

Reinheit: By hplc: 98.24% (Typical Value in Batch COA)

Farbe und Form: white powder

Molekulargewicht: 466.52g/mol

Ref: 54-BIT1041

T-2 Toxin

CAS: 21259-20-1

T-2 Toxin (T-2 Mycotoxin) is a fungal secondary metabolite produced by various Fusarium species in feed and grains, which is highly toxic to reproduction and induces a variety of cardiovascular toxicities.T-2 Toxin is an inhibitor of peptidyl transferase (60s ribosomal subunit) binding and protein synthesis. T-2 Toxin is an inhibitor of peptidyl transferase (60s ribosomal subunit) binding and protein synthesis, induces TM4 cell dysfunction via ROS-induced apoptosis, inhibits DNA and RNA synthesis, and increases hepatic lipid peroxidation levels.

Formel: C₂₄H₃₄O₉

Reinheit: 98%

Farbe und Form: White Needles From Benzene & Skellysolve B; Acetate Deriv Amorphous Solid From Ether & Pentane Solid

Molekulargewicht: 466.52

Ref: TM-T13053

T-2 Toxin

Kontrolliertes Produkt

CAS: 21259-20-1

Applications T-2 Toxin is a tricothecene mycotoxin produced by fungi of the genus Fusarium. T-2 Toxin induces DNA damage and cell death on prolonged administration.Environmental contaminants; Food contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kim, C., et al.: Cancer Res., 57, 3115 (1997), Bottrel, R., et al.: Antimicrob. Agents Chemother., 1999, 43, 856 (1999), Murray, P., et al.: J. Immunol., 178, 2623 (2007), Choi, H., et al.: Toxicol. Appl. Pharmacol., 240, 46 (2009), Amuzie, C., et al.: Toxicol. Sci., 113, 412 (2010),

Formel: C₂₄H₃₄O₉

Farbe und Form: White Solid

Molekulargewicht: 466.52

Ref: TR-T002980

T-2 Toxin-13C4

Kontrolliertes Produkt

CAS: 21259-20-1

Formel: C₄C₂₀H₃₄O₉

Farbe und Form: Neat

Molekulargewicht: 470.492

Ref: TR-T002981