CAS 124-94-7
:Triamcinolona
Descripción:
Triamcinolona es un corticosteroide sintético con propiedades antiinflamatorias e inmunosupresoras, comúnmente utilizado en el tratamiento de diversas condiciones como alergias, asma y trastornos autoinmunes. Se caracteriza por su capacidad para inhibir la liberación de mediadores inflamatorios y modular las respuestas inmunitarias. La estructura química de Triamcinolona incluye un esqueleto esteroide, que contribuye a su actividad biológica y farmacocinética. Se administra típicamente por vías tópicas, orales o inyectables, dependiendo de la condición que se trate. Triamcinolona es conocido por su potencia relativamente alta en comparación con otros corticosteroides, y puede formularse en varias formas, incluyendo cremas, ungüentos y suspensiones inyectables. Su uso puede estar asociado con efectos secundarios, particularmente con el uso a largo plazo, como supresión adrenal, aumento de peso y mayor riesgo de infecciones. Al igual que con cualquier medicamento, es esencial usar Triamcinolona bajo supervisión médica para gestionar eficazmente los riesgos y beneficios potenciales.
Fórmula:C21H27FO6
InChI:InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
Clave InChI:InChIKey=GFNANZIMVAIWHM-OBYCQNJPSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](O)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Sinónimos:- (11Beta,16Alpha)-9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- (11β,16α)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-Δ1,4-pregnadiene-3,20-dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-Δ<sup>1,4</sup>-pregnadiene-3,20-dione
- 9-Alpha-Fluoro-11-Beta,16-Alpha,17-Alpha,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 9-Alpha-Fluoro-16-Alpha-Hydroxyprednisolone
- 9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-16α-hydroxyprednisolone
- Acetonide
- Adcortyl
- Aristocort
- Cinolone
- Cl 19823
- Delphicort
- Fluoxiprednisolone
- Fluoxyprednisolone
- Kenacort
- Kenacort AG
- Ledercort
- Mycolog
- Nsc 13397
- Omicilon
- Polcortolon
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11β,16α)-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-
- Rodinolone
- Triamcinlon
- Triamcinolon
- Triamcinolone Base
- Triancinolona
- Tricortale
- Ver más sinónimos
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Triamcinolone
CAS:Fórmula:C21H27FO6Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:394.44Triamcinolone
CAS:TriamcinoloneFórmula:C21H27FO6Pureza:99.5%Forma y color:White SolidPeso molecular:394.17917Triamcinolone
CAS:Halogenated derivatives of adrenal cortical hormonesFórmula:C21H27FO6Forma y color:White Off-White PowderPeso molecular:394.17917Triamcinolone
CAS:Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Fórmula:C21H27FO6Pureza:98.66% - 99.60%Forma y color:White SolidPeso molecular:394.4311β,16α,17α,21-Tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
CAS:Fórmula:C21H27FO6Pureza:98%Forma y color:SolidPeso molecular:394.4339Ref: IN-DA0080N5
100mg37,00€250mg52,00€500mg62,00€1g68,00€2.5g123,00€5g163,00€10g209,00€25g345,00€50g517,00€Triamcinolone
CAS:Fórmula:C21H27FO6Pureza:97.5 - 102.5 %Forma y color:White to off-white crystalline powderPeso molecular:394.43Triamcinolone (Standard)
CAS:Triamcinolone (Standard) is the standard substance of Triamcinolone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to translocation of the ligand-receptor complex to the nucleus and induces expression of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both mediators of inflammation. In addition, pro-inflammatory cytokine production, including interleukin (IL)-1and IL-6, and the activation of cytotoxic T-lymphocytes is also inhibited. T-cells are prevented from making IL-2 and proliferating. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis through increasing Ikappa-B expression and curtailing activation of nuclear factor (NF)kappa-B.Fórmula:C21H27FO6Forma y color:SolidPeso molecular:394.43GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
CAS:Producto controlado- 105102-22-5
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Forma y color:MixtureTriamcinolone
CAS:Producto controladoTriamcinolone is a synthetic corticosteroid that reduces inflammation, suppresses the immune system, and relieves pain. It inhibits the production of cytokines and other inflammatory mediators by binding to specific receptors located in the cells of the immune system. Triamcinolone acetonide is an ester prodrug that is converted to triamcinolone in vivo. This drug has a long-term efficacy because it can be released slowly over time after intravitreal injection. The pharmacokinetic properties of triamcinolone are determined by its lipophilicity and water solubility. Triamcinolone acetonide has been shown to reduce inflammation in chronic arthritis, as well as reducing symptoms of eye disorders such as uveitis or glaucoma. This drug also prevents tumor growth by inhibiting protein synthesis and gene expression at the level of transcription, which leads to decreased cell proliferation or apoptosis.Fórmula:C21H27FO6Pureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:394.43 g/mol
