CAS 73771-04-7
:Prednicarbato
Descripción:
Prednicarbato es un corticosteroide sintético utilizado principalmente en dermatología por sus propiedades antiinflamatorias e inmunosupresoras. Se caracteriza por su capacidad para reducir la inflamación y aliviar los síntomas asociados con diversas condiciones de la piel, como el eczema y la psoriasis. Prednicarbato funciona inhibiendo la liberación de mediadores inflamatorios y modulando las respuestas inmunitarias. La sustancia se formula típicamente como una crema o ungüento tópico, permitiendo un tratamiento localizado con una mínima absorción sistémica. Su estructura química presenta un esqueleto esteroide, que es esencial para su actividad biológica. Prednicarbato es conocido por su potencia relativamente baja en comparación con otros corticosteroides, lo que lo hace adecuado para áreas de piel sensible. Además, tiene un perfil de seguridad favorable, con un menor riesgo de efectos secundarios como la atrofia cutánea cuando se utiliza según lo indicado. Al igual que con cualquier corticosteroide, es importante seguir las pautas de uso para minimizar los posibles efectos adversos y garantizar resultados de tratamiento efectivos.
Fórmula:C27H36O8
InChI:InChI=1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1
Clave InChI:InChIKey=FNPXMHRZILFCKX-KAJVQRHHSA-N
SMILES:C(COC(CC)=O)(=O)[C@]1(OC(OCC)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H]
Sinónimos:- (11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- Brd-K46137903
- Dermatop
- EsCort
- Hoe 777
- Prednicarbat
- Prednicarbate
- Prednicarbato
- Prednisolone 17-(ethyl carbonate) 21-propionate
- Prednitop
- Regenit
- S 77-0777
- 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3,20-dioxopregna-1,4-dien-21-yl propanoate
- (11beta)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3,20-dioxopregna-1,4-dien-21-yl propanoate
- 73771-04-7
- Ver más sinónimos
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Pureza (%)
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100
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50
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95
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100
Se han encontrado 15 productos.
PREDNICARBATE FOR PEAK IDENTIFICATION CRS
CAS:PREDNICARBATE FOR PEAK IDENTIFICATION CRSForma y color:Added AddedPREDNICARBATE FOR SYSTEM SUITABILITY A CRS
CAS:PREDNICARBATE FOR SYSTEM SUITABILITY A CRSFórmula:C27H36O8Forma y color:AddedPeso molecular:488.5699Prednicarbate
CAS:Adrenal cortical hormones and their derivatives nesoiFórmula:C27H36O8Forma y color:White Off-White PowderPeso molecular:488.24102Prednicarbate
CAS:Prednicarbate (Hoe 777), a corticosteroid, has antipruritic, anti-inflammatory effects, reduces lymphocytes, and inhibits vasodilators.Fórmula:C27H36O8Pureza:99.88%Forma y color:White SolidPeso molecular:488.57Prednicarbate
CAS:Fórmula:C27H36O8Pureza:≥ 98.0%Forma y color:White crystalline powderPeso molecular:488.57GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
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Forma y color:MixturePrednicarbate
CAS:Producto controladoApplications Topical anti-inflammatory agent. Glucocorticoid.
References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),Fórmula:C27H36O8Forma y color:NeatPeso molecular:488.57Prednicarbate - EP
CAS:Producto controladoPrednicarbate is an alopecia areata drug that is a corticosteroid. Prednicarbate is a prodrug, which means it needs to be converted by the liver into prednisolone before it can take effect. Prednicarbate has been shown to reduce the activity of disease-causing cells and to have anti-inflammatory properties. It does this by binding to glucocorticoid receptors on the surface of cells and inhibiting the production of inflammatory substances. Prednicarbate has been shown to have anti-inflammatory effects in animal models for inflammatory skin diseases, such as glomerular filtration rate and receptor binding. Prednicarbate may also suppress epidermal growth factor, leading to less cell proliferation in hair follicles.Fórmula:C27H36O8Pureza:97.0 To 102.0 Area-%Forma y color:White PowderPeso molecular:488.57 g/molPrednicarbate,USP
CAS:Producto controladoPrednicarbate, USP is a drug that belongs to the class of corticosteroids. It has been used to treat alopecia areata as well as inflammatory skin diseases such as psoriasis, atopic dermatitis, and seborrheic dermatitis. Prednicarbate, USP functions by inhibiting the production of prostaglandins in the skin. This action reduces inflammation and protects against damage to the epidermal barrier. Prednicarbate, USP has also been shown to inhibit phospholipase A2 activity in vitro and has a favorable chemical stability profile. The drug is metabolized through glucuronidation in humans and animals. Prednicarbate is highly lipophilic with a high affinity for fatty acids which may lead to its accumulation in adipose tissue. The drug also binds to receptors on inflammatory cells which may contribute to its anti-inflammatory properties.Fórmula:C27H36O8Pureza:Min. 95%Peso molecular:488.57 g/mol
